Nonconvulsive status epilepticus featuring ictal paresis mimicking a stroke.
Philippe Gélisse, Pierre Henri Lefevre, Rosalie Boitet et al.
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From the abstract
Wilson (1928) and Lennox (1960) described ictal paresis (IP) occurring during prolonged seizures that correspond to the modern definition of nonconvulsive status epilepticus (NCSE). This study aims to characterize this NCSE variant and clearly distinguish it from an acute stroke.
Reported results
Among the six patients, four had hemicorporeal deficits and two had isolated arm deficits. Other manifestations included sensory disturbances in three cases, mutism in five cases, and hemianopia in four cases. Two patients displayed perioral paresthesia. EEG showed ictal-interictal continuum patterns in three cases and focal/regional slowing in the other three.
Authors' conclusions
IP represents an under-recognized manifestation of NCSE. This study shows that perfusion-based neuroimaging is more sensitive than EEG for detecting ictal activity in this setting. We advocate for the routine inclusion of ASL sequences in the neuroimaging evaluation of patients with a suspected stroke and negative DWI findings.