A randomised, participant- and assessor-blinded, sham-controlled trial investigating acupuncture for disorders of gut-brain interaction in children (P-GAP).
BMJ OpenSep 22, 2026 (epub)
Ashish Chogle, Morris Gordon, Ruth McCarty et al.
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In 30 seconds
This randomized, participant- and assessor-blinded, sham-controlled trial investigates the efficacy of acupuncture for disorders of gut-brain interaction (DGBIs) in 96 children aged 8-17 years. The primary outcome is adequate pain relief, defined as a ≥30% reduction in mean abdominal pain severity on the 11-point Numerical Rating Scale from baseline to follow-up at weeks 12-14.
Key findings
- Participants will be randomized 1:1 to receive either standardised acupuncture or sham acupuncture.
- The primary outcome measures a ≥30% reduction in mean abdominal pain severity.
- Secondary outcomes include changes in pain frequency and health-related quality of life.
Why it matters
DGBIs are prevalent in children and can lead to significant morbidity. Effective treatment options are limited, making the evaluation of acupuncture as a potential therapeutic approach important for improving patient outcomes.