Multiple organ failure following severe heat stroke complicated by AMSAN-type Guillain-Barré syndrome: a case report and literature review.
Yu Zhang, Jiwei Yin, Jie Lu et al.
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Case in brief
A 57-year-old man developed confusion and hyperthermia while hiking, leading to a diagnosis of severe heat stroke and subsequent multiple organ failure. During recovery, he exhibited reduced muscle tone and sensory disturbances in all limbs, resulting in a diagnosis of AMSAN-type Guillain-Barré syndrome. His condition improved with plasma exchange, intravenous immunoglobulin, and rehabilitation.
What made this case unusual
The development of Guillain-Barré syndrome during recovery from severe heat stroke is a rare association, highlighting the potential immune dysregulation triggered by heat-related injuries.
Diagnostic / clinical pearl
Clinicians should be vigilant for Guillain-Barré syndrome in patients showing progressive neurological deficits during the recovery phase of heat stroke.
Why it matters
This case underscores the importance of timely neurophysiological and cerebrospinal fluid assessments for early diagnosis and intervention in similar cases.