Alzheimer's disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis of epidemiology and associated factors.
BMJ OpenSep 23, 2026 (epub)
Mantaka Rahman, Tamal Saha, Md Abu Jaher Nayeem et al.
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In 30 seconds
This systematic review and meta-analysis examined the prevalence and associated factors of Alzheimer's disease and related dementias (AD/ADRDs) in South and Southeast Asia, analyzing data from 31 studies. The overall estimated prevalence of dementia was 3.0%, with Alzheimer's at 2.0%. Notably, AD prevalence in low- and middle-income countries was 3.0%, increasing to 8.0% post-2010.
Key findings
- The overall estimated prevalence of dementia was 3.0% (95% CI 2.0% to 5.0%).
- Alzheimer's disease prevalence was 2.0% (95% CI 1.0% to 4.0%).
- Older adults had higher odds of AD (OR: 3.98, 95% CI 1.77% to 8.99%).
- AD prevalence increased to 8.0% after 2010 (95% CI 5.0% to 14.0%).
Why it matters
The rising prevalence of Alzheimer's disease and related dementias in South and Southeast Asia highlights the urgent need for targeted prevention and care strategies, particularly in low- and middle-income countries where resources may be limited.