From dental adhesives to injectable hemostats: a scoping review of antimicrobial biomaterials for oral soft-tissue bleeding.

In 30 seconds

This scoping review examines antimicrobial biomaterials for managing oral soft-tissue bleeding, focusing on injectable materials that provide rapid hemostasis and antimicrobial protection. The review synthesizes findings from 13 primary studies, revealing a 32%-42% reduction in hemostasis time compared to commercial controls, primarily in low-pressure models.

Key findings

• Injectable materials showed a 32%-42% reduction in hemostasis time compared to commercial controls.
• Antimicrobial zones of inhibition ranged from 10 to 18 mm.
• Current materials are effective against planktonic, single-species cultures but not yet validated against complex oral biofilms.

Why it matters

Understanding the effectiveness of these emerging biomaterials can enhance the management of acute oral hemorrhage in emergency settings, potentially improving patient outcomes and reducing complications associated with traditional methods.