Global, Regional, and Country Incidence of Peritoneal Dialysis-Associated Peritonitis in the Contemporary Peritoneal Dialysis Practice: A Systematic Review and Meta-Analysis.
Surapon Nochaiwong, Chidchanok Ruengorn, Kajohnsak Noppakun et al.
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In 30 seconds
This systematic review and meta-analysis estimated the global incidence of peritoneal dialysis-associated peritonitis, analyzing data from over 132,000 patients across 37 countries. The global incidence rate was found to be 0.31 episodes per patient-year, with significant regional variations. The study highlights the need for improved practices to enhance patient outcomes in peritoneal dialysis.
Key findings
- The global incidence rate of PD-associated peritonitis was 0.31 (0.28-0.34) episodes per patient-year.
- The highest regional incidence was 0.99 (0.68-1.45) in the African Region.
- South Africa, Portugal, and Sri Lanka had the highest country-specific incidence rates.
- Gram-positive bacteria were the most common causative microorganisms, with a pooled incidence rate of 0.127 (0.113-0.142).
Why it matters
Understanding the incidence rates of peritoneal dialysis-associated peritonitis is crucial for clinicians to identify high-risk populations and implement targeted interventions. This knowledge can guide improvements in patient management and care standards across different regions.