Effects of exercise interventions on gait, motor function, and balance in patients with Parkinson's disease: A meta-analysis with clinical implications.
Chengshuo Zhang, Zhen Jia, Yongdi Wang et al.
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In 30 seconds
This meta-analysis evaluated the effects of exercise interventions on gait, motor function, and balance in 714 patients with Parkinson's disease. The study found that exercise significantly reduced Freezing of Gait Questionnaire scores (SMD = -0.62) and Unified Parkinson's Disease Rating Scale Part III scores (SMD = -0.80), while improving Berg Balance Scale scores (SMD = 0.85).
Key findings
- Exercise interventions reduced Freezing of Gait Questionnaire scores (SMD = -0.62).
- Unified Parkinson's Disease Rating Scale Part III scores decreased significantly (SMD = -0.80).
- Berg Balance Scale scores improved with exercise (SMD = 0.85).
- Mini-BESTest outcomes showed no statistically significant change (SMD = 0.23).
Why it matters
Understanding the impact of exercise on motor function and balance in Parkinson's disease can guide clinicians in developing rehabilitation programs that enhance patient mobility and quality of life.
What to keep in mind
The included trials had methodological limitations, with 16 trials showing some concerns and 4 rated as high risk of bias.