Unusual pelvic mass in a young adult: prostatic Ewing's sarcoma with distant metastases.
Lakshmi Kandhan L, Venkata Ramana K, Rubina Singh et al.
✦ AI-curated · Sources linked
Case in brief
A man in his 20s presented with urinary obstruction, constipation, and leg pain. Imaging revealed a bulky pelvic mass from the prostate, leading to bilateral hydroureteronephrosis. Histological analysis confirmed Ewing's sarcoma. Staging PET-CT showed widespread metastases. The patient received chemotherapy and achieved complete metabolic remission, allowing for colostomy reversal and ongoing surveillance.
What made this case unusual
Primary Ewing's sarcoma originating in the prostate is exceptionally rare, with only isolated cases previously documented.
Diagnostic / clinical pearl
Clinicians should consider rare sarcomas like Ewing's in young men presenting with pelvic masses, especially when serum PSA levels are normal.
Why it matters
This case underscores the importance of timely systemic therapy in achieving durable responses in rare malignancies.