Effectiveness and safety of ultrasound-guided quadratus lumborum block combined with low-dose spinal anesthesia versus general anesthesia in percutaneous nephrolithotomy: a randomized controlled trial.
Mohamed Abdelrahman Alhefnawy, Ahmed Abdelrahman El-Tawansy, Zeinab M Ewes et al.
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In 30 seconds
This randomized controlled trial evaluated the effectiveness and safety of ultrasound-guided quadratus lumborum block (QLB) combined with low-dose spinal anesthesia (LDSA) versus general anesthesia (GA) in 70 adults undergoing percutaneous nephrolithotomy (PCNL). The study found that Group Q had significantly lower postoperative pain scores and opioid consumption, with median pethidine usage of 70 mg compared to 105 mg in Group G (p < 0.001).
Key findings
- Postoperative pain scores were significantly lower in Group Q during the first 8 hours (all p < 0.001).
- Median pethidine consumption was lower in Group Q at 70 mg versus 105 mg in Group G (p < 0.001).
- 82.8% of Group Q reported satisfaction compared to 8.6% in Group G (p < 0.001).
- Stone clearance rates were comparable between groups (p = 0.348).
Why it matters
The findings suggest that combining QLB with LDSA can enhance postoperative pain management and patient satisfaction in PCNL procedures, potentially leading to reduced opioid use and improved recovery experiences.