Effects of blood flow restriction combined with visual feedback training on lower limb function and the serum levels of BDNF and VEGF in patients with stroke.
Hai Jiang, Chengzhuo Yang, Pan Wang et al.
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In 30 seconds
This randomized controlled trial examined the effects of blood flow restriction training (BFRT) combined with visual feedback training (VFT) on lower limb function and serum levels of BDNF and VEGF in 40 hospitalized stroke patients. After 4 weeks, the experimental group showed significantly greater improvements in muscle strength, balance, and serum biomarker levels compared to the control group, indicating enhanced neurovascular plasticity.
Key findings
- The experimental group showed significantly greater improvements in MMT, FMA-LE, MBI, and FAC scores compared to the control group after 4 weeks.
- TUGT performance improved significantly in both groups, with the experimental group demonstrating greater improvement.
- Serum levels of BDNF and VEGF increased significantly in both groups, with greater increases in the experimental group.
Why it matters
The findings suggest that combining BFRT with VFT may enhance rehabilitation outcomes for stroke patients, improving functional recovery and potentially supporting neuroplasticity through increased serum levels of key growth factors.