Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.
Shobhit Raj, Renuka Suvarna, Girish Thunga et al.
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In 30 seconds
This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM). Analyzing data from seven studies involving 1,359 participants, the pooled prevalence of confirmed sarcopenia was found to be 27.4% (95% CI 18.9% to 37.9%). The study highlights the need for increased clinical awareness regarding sarcopenia in this population.
Key findings
- Pooled prevalence of confirmed sarcopenia was 27.4% (95% CI 18.9% to 37.9%).
- Severe sarcopenia prevalence was 11.0% across five studies.
- Sarcopenic obesity prevalence was 25.2% across four studies.
- Hypertension and diabetes duration ≥10 years were positively associated with sarcopenia.
Why it matters
Understanding the prevalence of sarcopenia in patients with T2DM is crucial for clinicians, as it can impact treatment strategies and patient outcomes. Increased awareness may lead to better management of muscle health in this population.
What to keep in mind
Certainty of prevalence estimates was very low, and the prediction interval was wide, indicating high variability.