16S rRNA Datasets of Gut Microbiota in Stent-Based Diverting Technique and Ileostomy from A Prospective, Open-Label, Multicenter Randomized Controlled Trial.
Sci DataSep 30, 2026 (epub)
Zhongyu Wu, Yifan Tong, Weiping Chen et al.
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In 30 seconds
This study presents a 16S rRNA amplicon dataset from a multicenter randomized controlled trial involving 80 patients undergoing either a stent-based diverting technique (SDT) or ileostomy after rectal cancer surgery. The analysis revealed significant differences in gut microbial composition and diversity, with implications for postoperative recovery and complications.
Key findings
- Patients were randomized to SDT (n = 37) or ileostomy (n = 43).
- Fecal samples were collected preoperatively and on postoperative day 90.
- Differential metabolic pathways were detected post-surgery.
- The dataset allows for independent reprocessing and cross-study comparisons.
Why it matters
Understanding the impact of different surgical techniques on gut microbiota can inform postoperative care strategies and potentially reduce complications associated with dysbiosis, enhancing recovery in patients undergoing rectal cancer surgery.