Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis.

Depress AnxietySep 29, 2026 (epub)
Clinical ResearchGeriatricsPsychiatryOpen access

Ping Ni, Li Liu, Li Zeng et al.

✦ AI-curated · Sources linked

In 30 seconds

This meta-analysis examined the relationship between dual sensory impairment (DSI) and depressive symptoms in three aging cohorts: CHARLS, HRS, and ELSA. The study found that DSI was significantly associated with increased odds of depressive symptoms, with odds ratios of 1.24, 2.04, and 2.40 across the cohorts. Mediation analyses indicated that reduced social engagement and cognitive decline partially mediated this association.

Key findings

  • DSI was associated with higher odds of depressive symptoms: OR = 1.24 in CHARLS, OR = 2.04 in HRS, OR = 2.40 in ELSA.
  • Meta-analysis confirmed the association with an overall OR of 1.73 and HR of 1.30.
  • Reduced social engagement mediated 2.31%-6.35% of the association, while cognitive decline mediated 5.72%-14.00%.

Why it matters

Understanding the link between dual sensory impairment and depressive symptoms is crucial for developing targeted interventions. Clinicians should consider sensory health as a factor influencing mental health in older adults, potentially guiding preventive strategies and treatment plans.

Source

Published in Depress Anxiety. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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