Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.

Rheumatol IntSep 30, 2026 (epub)

Nurten Gizem Tore, Christine A Pellegrini, Kailyn Horn et al.

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In 30 seconds

This secondary analysis of a randomized controlled trial examined whether baseline physical function influenced the response to a telephone-delivered Walk With Ease (WWE-T) intervention in 267 adults with arthritis. The study found that while baseline function did not moderate changes in steps/day, higher chair-stand performance was linked to increased steps, with an increase of 731 steps/day at 6 weeks in the high-repetition WWE-T subgroup.

Key findings

  • Higher chair-stand performance was associated with more steps/day across follow-up (P = 0.0003).
  • In the high-repetition WWE-T subgroup, steps/day increased by 731 at 6 weeks (95% CI 281 to 1182).
  • Higher walking endurance was associated with more steps/day (P < 0.0001).

Why it matters

Understanding how baseline physical function affects responses to physical activity interventions can help tailor rehabilitation strategies for adults with arthritis, potentially improving their mobility and quality of life.

Source

Published in Rheumatol Int. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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