Primary malignant mesothelioma of the tunica vaginalis presenting as hydrocele: imaging pitfalls.

BMJ Case RepOct 1, 2026 (epub)

Jatin Naidu, Nikhil G Joseph, Mai Mohammed et al.

✦ AI-curated · Sources linked

Case in brief

A man in his late 70s presented with a progressive, painless scrotal swelling initially diagnosed as a simple hydrocele via ultrasound. During surgery, friable nodules on the tunica vaginalis were biopsied, revealing malignant epithelioid mesothelioma. Staging CT confirmed no pleural or peritoneal disease, indicating a primary origin from the tunica vaginalis.

What made this case unusual

This case is notable for the rare occurrence of primary malignant mesothelioma of the tunica vaginalis, which is typically a site of secondary spread from the peritoneum.

Diagnostic / clinical pearl

Clinicians should maintain a high index of suspicion for malignancy in cases of scrotal swelling, especially when imaging findings do not correlate with intraoperative findings.

Why it matters

This case underscores the limitations of ultrasound in diagnosing scrotal masses and the need for careful evaluation when imaging results are inconsistent with clinical presentation.

Source

Published in BMJ Case Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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