Thyrotoxicosis-Associated Cholestatic Jaundice in a Patient With Incidental Gallstone Disease: A Case Report and Literature Review.

Am J Case RepOct 2, 2026 (epub)
Case ReportEndocrinologyGastroenterology

Zakaria Yahya Khawaji, Basim Saleh Samman, Basem Younis Alturkistany et al.

✦ AI-curated · Sources linked

Case in brief

A 62-year-old woman presented with right upper quadrant pain, weight loss, and jaundice. Laboratory tests indicated cholestatic liver injury, and imaging revealed a solitary gallstone and signs of right-sided heart failure. Thyroid function tests confirmed primary hyperthyroidism due to toxic multinodular goiter. Treatment with methimazole resulted in significant improvement of jaundice, suggesting thyrotoxicosis as a key factor in her condition.

Diagnostic / clinical pearl

Clinicians should consider hyperthyroidism as a potential cause of cholestatic jaundice, especially in patients with atypical presentations.

Source

PubMed · PMID 42823791

Published in Am J Case Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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