Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery.
Lasers Med SciOct 2, 2026 (epub)
Aya Fahim, Elham Saied, Marwa S El-Mesidy
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the effectiveness of fractional CO₂ laser treatment alone versus its combination with botulinum toxin A in 16 patients with post-burn hypertrophic scars. The study found that intralesional botulinum toxin A combined with fractional CO₂ laser resulted in the greatest reduction in Vancouver Scar Scale scores, achieving a reduction of -58.25%.
Key findings
- Intralesional botulinum toxin A combined with fractional CO₂ laser achieved a VSS reduction of -58.25%.
- Fractional CO₂ laser monotherapy and laser-assisted drug delivery showed less efficacy compared to the combination treatment.
- The combination treatment improved scar pliability, contour, and patient comfort significantly.
Why it matters
Understanding the most effective treatment options for hypertrophic scars is crucial for improving patient outcomes. This study highlights the potential benefits of combining therapies to enhance scar management.