Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.
Clin Interv AgingSep 28, 2026 (epub)
Chawen Ding, Linyu Li, Gaoming Li et al.
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In 30 seconds
This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke. The study found that EVT led to a favorable shift in 90-day modified Rankin scale (mRS) scores compared to standard medical treatment (SMT), with an adjusted common odds ratio of 2.83. Additionally, EVT was associated with lower 90-day mortality.
Key findings
- EVT resulted in a favorable shift in 90-day mRS scores compared to SMT (adjusted common odds ratio 2.83).
- 90-day mortality was significantly lower in the EVT group (P=0.009).
- The rate of any intracerebral hemorrhage was significantly higher in the EVT group (P=0.001).
- Increasing age did not modify the treatment effect of EVT.
Why it matters
The findings suggest that EVT can improve functional outcomes and reduce mortality in elderly patients with large ischemic stroke, highlighting its potential role in this age group despite the associated risks.