Diagnostic yield of Franseen biopsy needles in endoscopic ultrasound-guided tissue acquisition: a systematic review and meta-analysis.

In 30 seconds

This systematic review and meta-analysis evaluated the diagnostic performance of Franseen biopsy needles compared to standard needles in endoscopic ultrasound-guided tissue acquisition among adult patients. The study found that Franseen needles significantly improved sample adequacy (OR 2.83) and histological core procurement (OR 5.02), while maintaining similar adverse event rates.

Key findings

• Franseen needles had higher odds of sample adequacy compared to standard needles (OR 2.83; 95% CI [2.13-3.75]).
• Diagnostic sensitivity and specificity for Franseen needles were 0.92 and 0.98, respectively.
• Optimal histological cores were procured in 89% of patients using Franseen needles.
• Franseen needles reduced the number of passes per patient by an average of 0.36.

Why it matters

Improving sample adequacy and histological core procurement can enhance diagnostic accuracy in gastrointestinal and pancreaticobiliary lesions, potentially leading to better patient outcomes. Understanding the benefits of different biopsy techniques is crucial for optimizing diagnostic strategies.