Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial.
Seyed Yaser Ghelmani, Seyede Hamide Rajaie, Roghayeh Zare et al.
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In 30 seconds
This randomized double-blind placebo-controlled trial investigated the effects of rosehip fruit extract on orthostatic intolerance symptoms in 60 adults with type 2 diabetes and orthostatic hypotension. The study found that participants receiving rosehip had a prevalence ratio of 2.57 for no longer meeting diagnostic criteria for orthostatic hypotension compared to placebo, indicating significant symptom improvement.
Key findings
- 57 out of 60 participants completed the 4-week intervention.
- Rosehip group had a prevalence ratio of 2.57 for no longer meeting orthostatic hypotension criteria.
- Significant reductions in Orthostatic Intolerance Questionnaire scores were observed in the rosehip group (P = 0.001).
- Symptom improvement in the rosehip group exceeded predefined clinical relevance thresholds.
Why it matters
Orthostatic hypotension is a common complication in type 2 diabetes, leading to significant morbidity. This study suggests that rosehip supplementation may offer a novel approach to alleviate these symptoms, potentially improving patient quality of life.