Lymphocele After Radical Prostatectomy: A Systematic Review of Risk Factors and Quantitative Synthesis Preventive Strategies.
World J UrolOct 5, 2026 (epub)
Ömer Faruk Çavdar, Burak Akgül, Furkan Güldibi et al.
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In 30 seconds
This systematic review evaluated risk factors and preventive strategies for lymphocele formation after radical prostatectomy with pelvic lymph node dissection. It included 31 studies and found that peritoneal flap-based reconstruction significantly reduced symptomatic lymphocele (RR 0.57, 95% CI 0.35-0.95). The review emphasizes a multifactorial approach to prevention.
Key findings
- High BMI and low fibrinogen were identified as potential preoperative risk factors for lymphocele.
- Peritoneal flap-based reconstruction reduced symptomatic lymphocele with a risk ratio of 0.57.
- A sensitivity analysis suggested an even larger effect of peritoneal reconstruction (RR 0.18).
- Preventive strategies like selective drain management were associated with fewer lymphatic complications.
Why it matters
Understanding the risk factors and effective preventive strategies for lymphocele formation can help clinicians optimize surgical techniques and postoperative care, potentially reducing complications and improving patient outcomes.