World's first case report of live birth following autologous ovarian tissue cryopreservation and transplantation in a patient with colon carcinoma.
Xiangyan Ruan, Juan Du, Muqing Gu et al.
✦ AI-curated · Sources linked
Case in brief
A 29-year-old woman with colon cancer underwent ovarian tissue cryopreservation prior to chemotherapy. After developing premature ovarian insufficiency, she received two transplantations of thawed ovarian cortex strips. Following the second transplantation, she conceived spontaneously and delivered a healthy baby girl, demonstrating the potential of ovarian tissue cryopreservation for fertility preservation in cancer patients.
Diagnostic / clinical pearl
Ovarian tissue cryopreservation and transplantation can restore ovarian function and enable conception in patients undergoing cancer treatment.
Why it matters
This case highlights the importance of fertility preservation strategies in young cancer patients, providing a viable option for those facing premature ovarian insufficiency.