Efficacy of US-guided Hydrodissection for Carpal Tunnel Syndrome: A Prospective Randomized Controlled Trial.

RadiologyOct 1, 2026

Anindita Bose, Anupama Tandon, Gopesh Mehrotra et al.

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In 30 seconds

This prospective randomized controlled trial evaluated the efficacy of three US-guided hydrodissection techniques for treating carpal tunnel syndrome (CTS) in adults with refractory symptoms. The study found that hydrodissection with normal saline alone led to sustained clinical improvement, with 85.7% of wrists achieving minimal clinically important difference in symptom severity at 24 weeks, comparable to the combination with corticosteroids.

Key findings

  • 85.7% of wrists in the hydrodissection group achieved minimal clinically important difference in BCTQ at 24 weeks.
  • Percentage reduction in median nerve CSA was 43% for hydrodissection alone and 46% with corticosteroid at 12 weeks.
  • Group receiving corticosteroids showed early improvement but no significant difference from baseline at 24 weeks.
  • No major complications were observed in any treatment group.

Why it matters

The findings suggest that US-guided hydrodissection with normal saline is an effective treatment for CTS, providing sustained symptom relief without the need for corticosteroids, which may help guide treatment decisions in clinical practice.

Source

Published in Radiology. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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