Outcomes after middle meningeal artery embolization using coils alone for chronic subdural hematoma: A systematic review and single-arm meta-analysis.
Matthan Tharakan, Steven G Stagg, Brandon De La Torre et al.
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In 30 seconds
This systematic review and single-arm meta-analysis evaluated the outcomes of coil-only middle meningeal artery embolization (MMAE) for chronic subdural hematoma (cSDH) in 397 patients across 10 studies. The pooled recurrence rate was 4.6%, and the reintervention rate was 7.5%. The findings suggest that coil-only MMAE may be a viable option, but the evidence is limited by substantial risk of bias.
Key findings
- The pooled recurrence rate after coil-only MMAE was 4.6% (95% CI, 1.7%-12.1%).
- The pooled reintervention rate was 7.5% (95% CI, 4.5%-12.3%).
- Procedure-related complications occurred at a pooled rate of 1.3% (95% CI, 0.5%-3.0%).
- Radiographic reduction > 50% was achieved in 76.7% (95% CI, 55.0%-89.8%) of cases.
Why it matters
Understanding the outcomes of coil-only MMAE for cSDH is crucial for clinicians considering this treatment option. The low rates of recurrence and complications may inform decision-making, although the evidence is not definitive.
What to keep in mind
Most studies included were retrospective and nonrandomized, with serious risk of bias and heterogeneous treatment contexts.