Atypical presacral masses in Currarino syndrome: a case series.
Ravi Ameet Patel, Rebecca Du, Erin Rowell et al.
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Case in brief
The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass. Pathologic examination identified a myxopapillary ependymoma associated with a retrorectal teratoma, a mature cystic teratoma, and a neuroendocrine tumor arising within a teratoma. The cases demonstrate that presacral lesions in this syndrome can include tumors beyond the commonly reported anterior meningoceles and teratomas. The authors emphasize that surgical management should be individualized and may require a multidisciplinary approach.
What made this case unusual
The cases included a myxopapillary ependymoma associated with a retrorectal teratoma and a neuroendocrine tumor arising within a teratoma—tumor types the authors identify as underrecognized or previously unreported in Currarino syndrome.
Diagnostic / clinical pearl
Do not assume a presacral mass in Currarino syndrome is an anterior meningocele or a conventional teratoma; pathologic assessment may reveal a broader range of lesions.
Why it matters
Recognizing this lesion heterogeneity supports thorough evaluation and individualized, often multidisciplinary, surgical planning.