Pediatric conjunctival papilloma managed with staged multimodal therapy: a case report.
Mohammadreza Sedaghat, Javad Sadeghi, Sahel Khazaei
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Case in brief
A 4-year-old boy presented with multifocal conjunctival papillomatous lesions and was diagnosed with conjunctival papilloma. Topical and intralesional interferon alfa-2b were used before surgery to reduce lesion size. Residual disease was managed with limited excision and intraoperative mitomycin C. The clinical course was favorable, with preservation and progressive restoration of conjunctival architecture; no recurrence was evident at 2 years of follow-up.
What made this case unusual
The case used preoperative interferon-mediated debulking to enable limited excision of multifocal disease, with the aim of preserving healthy conjunctival tissue in a young child.
Diagnostic / clinical pearl
For multifocal pediatric conjunctival papilloma, staged medical debulking followed by targeted excision may allow tissue preservation while achieving disease control, as illustrated by this case.