Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.

PLoS OneOct 13, 2026 (epub)

Deloris J Veney, Lai Wei, Jaden Miller et al.

✦ AI-curated · Sources linked

In 30 seconds

This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings. Of 203 participants who completed all surveys, video message-specific knowledge (VMSK) improved significantly from before viewing to immediately afterward and remained improved after TGT results were returned (overall p < 0.0001). General genomic knowledge/understanding did not significantly change (p = 0.41), nor did trust in physicians/providers (p = 0.73). The VMSK improvement was consistent across all cohorts.

Key findings

  • VMSK improved significantly and durably across survey timepoints (overall p < 0.0001).
  • General genomic knowledge/understanding did not significantly change (p = 0.41), and trust in physicians/providers did not change significantly (p = 0.73).
  • The VMSK improvement was consistent across all cohorts (all p ≤ 0.0001).
  • Four VMSK questions improved significantly, including those on treatment decisions, incidental germline findings, and insurance coverage of testing.

Why it matters

Patient education before TGT is often omitted despite established guidelines. This study suggests a brief video can improve knowledge of its specific messages across cancer types and care settings, including information relevant to treatment decisions, incidental findings, and insurance coverage. The lack of change in broader genomic knowledge or provider trust indicates that the observed benefit was focused rather than general.

What to keep in mind

The abstract reports survey outcomes but does not describe a comparison group; the findings therefore do not establish how the video compares with other education approaches.

Source

Published in PLoS One. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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