[ 18 F]AlF-NOTA-FAPI-04 PET/CT for Incidental Detection of a Benign Phyllodes Tumor in a Patient With Prior Colon Cancer.

Clin Nucl MedOct 20, 2026 (epub)
Case ReportNuclear MedicineRadiology (Diagnostic)Pathology (Anatomic & Clinical)Oncology (Medical)

Li Juan Feng, Hao Wang, Wei Zhang

✦ AI-curated · Sources linked

Case in brief

A 68-year-old woman with a history of colon cancer had a right breast nodule detected incidentally on routine contrast-enhanced CT, where it showed moderate enhancement. Subsequent [18F]AlF-NOTA-FAPI-04 PET/CT demonstrated intense focal uptake (SUVmax: 6.63). Histologic examination identified the lesion as a benign phyllodes tumor.

What made this case unusual

The benign breast tumor showed intense focal FAPI uptake, illustrating that this imaging finding is not specific to malignancy.

Diagnostic / clinical pearl

In a cancer survivor, an FAPI-avid lesion may be benign; histologic confirmation can help prevent unnecessary treatment.

Source

PubMed · PMID 42912540

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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