Comparison of Sevoflurane and Propofol-Fentanyl for Laryngeal Mask Airway Insertion in Pediatric cases.
Meera G, Kumar C Prashanth, Uppangala Chaitra et al.
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In 30 seconds
This prospective, single-blinded randomized study compared sevoflurane with intravenous propofol-fentanyl for laryngeal mask airway (LMA) insertion in 60 children aged 4–12 years with ASA physical status I or II undergoing elective surgery. Jaw relaxation took longer with sevoflurane than with propofol-fentanyl (108.41 ± 6.90 vs 53.35 ± 4.12 seconds; p < 0.05), as did LMA insertion (118.96 ± 6.65 vs 63.19 ± 4.31 seconds; p < 0.05). Sevoflurane was associated with better hemodynamic stability, and the authors reported comparable safety profiles.
Key findings
- Jaw relaxation was slower with sevoflurane than propofol-fentanyl: 108.41 ± 6.90 vs 53.35 ± 4.12 seconds; p < 0.05.
- LMA insertion took longer with sevoflurane than propofol-fentanyl: 118.96 ± 6.65 vs 63.19 ± 4.31 seconds; p < 0.05.
- Sevoflurane showed better hemodynamic stability, with comparable safety profiles reported between groups.
Why it matters
The comparison highlights a trade-off between speed of airway placement and hemodynamic stability during pediatric anesthesia. These outcomes may inform consideration of induction approach when LMA insertion is planned, while the findings apply to the studied elective-surgery population and should be interpreted in light of the trial’s size and setting.
What to keep in mind
The study included 60 children and was single-blinded; the abstract does not report longer-term outcomes.