Anaesthetic Management of a Child with Chromosome 7q32.1 Microdeletion Undergoing Ligation of Patent Processus Vaginalis.
S Lal, E Khan, M Rasheed et al.
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Case in brief
A six-year-old boy with chromosome 7q32.1 microdeletion, autism spectrum disorder, attention deficit hyperactivity disorder, hypotonia and asthma underwent elective ligation of a patent processus vaginalis under general anaesthesia. Given the potential for perioperative respiratory adverse events and challenges with induction and emergence, the team used sevoflurane in oxygen, a laryngeal mask airway rather than endotracheal intubation, and avoided neuromuscular blockade while preserving spontaneous ventilation. The perioperative course was uneventful, with no respiratory complications.
What made this case unusual
The case describes anaesthetic management in a child with chromosome 7q32.1 microdeletion alongside autism, hypotonia and asthma, a combination that raised airway and behavioural considerations.
Diagnostic / clinical pearl
In this child, minimising airway stimulation, maintaining spontaneous ventilation and tailoring the approach to behavioural needs supported an uneventful anaesthetic course.