Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.

Medicine (Baltimore)Oct 23, 2026
Case ReportOncology (Medical)NephrologyRadiology (Diagnostic)Pathology (Anatomic & Clinical)Open access

Xintong Li, Jia Li, Shijie Sun et al.

✦ AI-curated · Sources linked

Case in brief

A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine. Ultrasonography, CT, MRI, and contrast-enhanced ultrasonography all suggested renal cell carcinoma. An ultrasound-guided renal needle biopsy was performed, and histopathology established primary renal diffuse large B-cell lymphoma.

What made this case unusual

Multiple imaging modalities, including contrast-enhanced ultrasonography, supported an initial diagnosis of renal cell carcinoma, while biopsy revealed primary renal diffuse large B-cell lymphoma.

Diagnostic / clinical pearl

Imaging may not distinguish primary renal lymphoma from renal cell carcinoma; tissue diagnosis can resolve this diagnostic uncertainty.

Source

PubMed · PMID 42937761Free full text on PubMed Central

Published in Medicine (Baltimore). This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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