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1998 articles
October 202624
A Case of Primary Intramedullary Infantile Fibrosarcoma With an RBPMS::NTRK3 Fusion and Response to Larotrectinib.
A 4-week-old infant presented with rapidly progressive cervical myelopathy due to primary intramedullary infantile fibrosarcoma.
Well-differentiated SMARCB1-deficient Pancreatic Malignancy With Indolent Liver Metastases.
A 66-year-old woman underwent distal pancreatectomy for a pancreatic tail malignancy, later developing liver metastases six years post-surgery.
The missing evidence: Stricturing Crohn's disease in clinical trials, a systematic review.
This systematic review assessed the efficacy of biologic and small-molecule therapies in stricturing Crohn's disease (CD) among adults.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
Temporary Mesocaval Bypass During Pancreaticoduodenectomy for Pancreatic Cancer With Portal Vein Occlusion: A Case Report.
A 79-year-old man with locally advanced pancreatic cancer and complete portal vein occlusion underwent pancreaticoduodenectomy after showing a favorable response to preoperative therapy.
Early-life liquefied petroleum gas cooking intervention and lung function in Guatemalan children: a randomized clinical trial.
This randomized clinical trial assessed the impact of an early-life liquefied petroleum gas cooking intervention on lung function in Guatemalan children.
Three versus six weeks of corticosteroids for mild immune-related pneumonitis: a randomized trial.
This randomized controlled trial evaluated the efficacy of a 3-week versus a 6-week corticosteroid taper in patients with mild immune-related pneumonitis.
Association of white blood cell count with treatment response to cefepime versus piperacillin-tazobactam.
This randomized controlled trial analyzed the impact of white blood cell (WBC) count on the effectiveness of cefepime versus piperacillin-tazobactam in treating sepsis.
Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.
This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.
Pulmonary specialist health coach consultation model: a randomized controlled trial.
This randomized controlled trial evaluated a pulmonary specialist health coach consultation model for low-income patients with asthma and/or COPD.
Envenomation by a Razi's viper, Macrovipera razii (Serpentes: Viperidae) in Iran: A neglected public health threat, report of two cases, and clinical implications.
Two men in Iran developed severe local injury after bites from Macrovipera razii. A 36-year-old man bitten on a finger received six vials of polyvalent antivenom but developed progressive necrosis, leaving permanent…
TMS-Derived Neurophysiological Measures of Corticospinal Excitability, Intracortical Excitability, and Interhemispheric Interactions Associated With Post-Stroke Motor Recovery: A Systematic Review.
This systematic review evaluated the relationship between TMS-derived neurophysiological measures and motor recovery in adults post-stroke, synthesizing data from 16 randomized controlled trials.
Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation.
This systematic review and meta-analysis pooled six randomized controlled trials comparing percutaneous left atrial appendage closure (LAAC) with oral anticoagulation in 7028 patients with nonvalvular atrial…
Modified One Anastomosis Gastric Bypass (OAGB) Versus Duodenojejunostomy for Treatment of Superior Mesenteric Artery Syndrome: A Randomized Controlled Trial.
This randomized controlled trial compared modified one anastomosis gastric bypass (OAGB) to duodenojejunostomy in 20 patients with superior mesenteric artery syndrome.
Tumor-Infiltrating Lymphocytes as a Predictor of Adjuvant Avelumab Efficacy in Patients with High-risk Triple-Negative Breast Cancer.
This phase III randomized controlled trial investigated the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) in 466 patients with high-risk early triple-negative breast cancer (TNBC) receiving…
Social Determinants of Health and Neurobiology Across the Schizophrenia Course: A Systematic Review.
This systematic review examined associations between adverse social determinants of health and brain measures in people across the schizophrenia spectrum, including those at elevated risk.
Immersive Virtual Reality and Anxiety, Nausea, and Vomiting in Children With Cancer: An RCT.
This randomized controlled trial evaluated the impact of immersive virtual reality (IVR) on anxiety, anticipatory nausea, and chemotherapy-induced nausea and vomiting (CINV) in pediatric cancer patients aged 6-12…
Preoperative High-Dose Corticosteroids in Digestive Cancer Surgery: A Randomized Clinical Trial.
This multicenter, double-blind, placebo-controlled superiority randomized trial assessed whether preoperative high-dose corticosteroids improve outcomes after elective, curative-intent surgery for digestive cancer.
The predictive value of early-pregnancy mean platelet volume for preeclampsia: A meta-analysis.
This meta-analysis assessed whether mean platelet volume (MPV) measured before 20 weeks’ gestation is associated with subsequent preeclampsia.
Bimekizumab efficacy in male and female patients with axial spondyloarthritis: 52-week results from the phase 3 BE MOBILE trials.
This post hoc analysis of two phase 3 randomised trials assessed sex-based differences in bimekizumab response among patients with radiographic or non-radiographic axial spondyloarthritis.
Cross-Linked Chondroitin Sulfate Adhesion Barrier System in Open Rectal Resection: A Randomized Clinical Trial.
This multicenter, prospective, randomized, open-label trial with blinded endpoint assessment evaluated powdered cross-linked chondroitin sulfate (SI-449) in adults undergoing open rectal resection for rectal cancer.
Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed randomised trials of psychological and psychosocial interventions targeting auditory hallucinations in adults with schizophrenia spectrum disorders.
Avutometinib, Abemaciclib, and Fulvestrant in Patients with HR+/HER2- Metastatic Breast Cancer Previously Treated with CDK4/6 Inhibitor: A Single-Arm Phase I Trial.
This single-arm phase I trial evaluated the combination of avutometinib, abemaciclib, and fulvestrant in 16 patients with HR+/HER2- metastatic breast cancer who had previously progressed on CDK4/6 inhibitors.
Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.
A bilateral transtibial amputee had a modified tibiofibular synostosis (TFS) stump on the right and a conventional Burgess-type stump (BTS) on the left.
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