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1998 articles

October 202624

Clinical ResearchNeurologyOpen access

Gene-based association analysis of depression risk among European ancestry Parkinson's disease patients.

This gene-based association analysis and meta-analysis examined common and low-frequency genetic variants related to depression among European-ancestry patients with Parkinson’s disease (PD) in three population-based…

Hum GenetOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Global cognitive and verbal episodic memory impairment in the post-acute phase of anti-nmdar encephalitis: a systematic review and meta-analysis with narrative synthesis.

This systematic review and meta-analysis examined standardized cognitive outcomes in adults with cell-based-assay-confirmed anti-NMDAR encephalitis during the post-acute or convalescent phase.

Neurol SciOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Digital supportive care in prostate cancer: a systematic review.

This systematic review synthesised evidence on the perspectives and requirements of people affected by prostate cancer for patient-facing digital supportive care.

Support Care CancerOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

PD-1/ PD-l1 Inhibitors and Stereotactic Radiosurgery for Brain Metastases: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed efficacy and toxicity when PD-1/PD-L1 inhibitors were combined with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) for…

Clin Exp MetastasisOct 17, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Periconceptional and early-pregnancy exposure to SGLT2 inhibitors and congenital malformations: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed observational cohort evidence on preconception or early-pregnancy SGLT2 inhibitor exposure among women with type 2 diabetes.

EndocrineOct 17, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Gamma-irradiated amniotic membrane graft as an adjuvant to posterior colporrhaphy: an exploratory prospective single-arm clinical trial.

This exploratory prospective, single-arm pilot clinical trial evaluated gamma-irradiated amniotic membrane grafting during posterior colporrhaphy in 25 women with posterior compartment prolapse.

BMC Womens HealthOct 17, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Duration of single-agent perioperative antibiotic prophylaxis and postoperative meningitis after endoscopic endonasal skull base surgery: a systematic review and meta-analysis of 7,981 patients.

This systematic review and meta-analysis examined postoperative meningitis after endoscopic endonasal skull-base surgery in 7,981 patients across 14 studies using single-agent perioperative antibiotic prophylaxis.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Genetic correlates of corticobasal degeneration: a systematic review and meta-analysis.

This PRISMA-guided systematic review and meta-analysis synthesized genetic association studies of corticobasal degeneration (CBD), including 22 studies published between 2001 and 2025.

J NeurolOct 17, 2026Read summary
Clinical ResearchHematology

Non-Relapse Mortality With Bispecific Antibodies in Hematologic Malignancies: A Dual Systematic Review and Pharmacovigilance Analysis.

This systematic review and meta-analysis, supplemented by a pharmacovigilance analysis of FAERS, assessed non-relapse mortality (NRM) and other toxicities with bispecific antibodies in relapsed/refractory hematologic…

Hematol OncolOct 17, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Systematic review and meta-analysis on comparing treatment approaches of cervical fractures in ankylosing spondylitis to determine improvement in outcomes.

This systematic review and meta-analysis compared anterior, posterior, and combined surgical approaches for cervical fractures in patients with ankylosing spondylitis.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Microsurgical clipping versus Woven EndoBridge embolization for intracranial aneurysms: a systematic review and meta-analysis.

This systematic review and meta-analysis compared microsurgical clipping with Woven EndoBridge (WEB) embolization for ruptured and unruptured intracranial aneurysms.

Neurosurg RevOct 17, 2026Read summary
Case ReportRheumatologyOpen access

Tocilizumab for active rheumatoid arthritis in a patient with concomitant primary biliary cholangitis: a case based review.

A 59-year-old woman presented with highly active, seropositive rheumatoid arthritis and marked cholestatic biochemical activity. Evaluation identified active primary biliary cholangitis without advanced liver fibrosis.

Rheumatol IntOct 17, 2026Read case
Clinical ResearchOrthopedic Surgery

Patient-Reported Outcomes after Distal Radius Fractures Differ Across Geographic and Cultural Populations: A Global Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined whether patient-reported outcomes after volar locking-plate fixation of adult distal radius fractures varied across cultural and geographic populations.

J Orthop TraumaOct 17, 2026Read summary
Case ReportGeneral SurgeryOpen access

Anatomical Correction of Adult Intestinal Malrotation Using Kareem's Procedure: A Case Report.

A 26-year-old woman presented with sudden severe colicky central abdominal pain, non-bilious vomiting, and complete constipation; she had experienced a similar self-limited episode a month earlier.

Int Med Case Rep JOct 17, 2026Read case
Clinical ResearchOncology (Medical)Open access

Effectiveness of local ablative therapy combined with first-line tyrosine kinase inhibitors in epidermal growth factor receptor-mutated oligometastatic non-small cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed local ablative therapy (LAT) plus first-line tyrosine kinase inhibitors (TKIs) versus TKI alone in patients with EGFR-mutated oligometastatic non-small cell lung cancer.

Clin Exp MetastasisOct 17, 2026Read summary
Case ReportOncology (Medical)Open access

Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.

A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.

J Cancer Res Clin OncolOct 16, 2026Read case
Clinical ResearchNephrology

Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.

This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.

J Med Internet ResOct 16, 2026Read summary
Case ReportPsychiatry

Clinical Improvement Following Multimodal Treatment in Depersonalization-Derealization Disorder: A Case Report.

A patient with depersonalization-derealization disorder presented with derealization, emotional blunting, poor memory, slowed reactions, and impaired attention.

J Vis ExpOct 16, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Lymphoplasmacytic Lymphoma Involving Marrow-Containing Submandibular Heterotopic Ossification: A Case Report and Literature Review.

A 77-year-old man presented with a gradually enlarging, increasingly uncomfortable calcified nodule in the left submandibular region.

Head Neck PatholOct 16, 2026Read case
Case ReportGastroenterology

Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.

A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia the day after starting atezolizumab plus bevacizumab.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportPulmonology

Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.

After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchMedical Genetics

The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.

This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportOncology (Medical)

WIN-MTB-2024002 - WIN International Molecular Tumor Board: A 52-year-old female with unmeasurable Stage IIIc colon cancer.

A 52-year-old woman with stage IIIc colon cancer had KRAS, TP53, IDH1, and APC mutations, high tumor PD-L1 expression, and elevated VEGFR1 and VEGFR3.

OncotargetOct 16, 2026Read case
Clinical ResearchEmergency Medicine

Neutrophil to lymphocyte ratio for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether the neutrophil-to-lymphocyte ratio (NLR) predicts delayed neurologic sequelae (DNS) after acute carbon monoxide poisoning.

Medicine (Baltimore)Oct 16, 2026Read summary

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