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2000 articles
October 202624
Increased mean corpuscular hemoglobin concentration: A case report as an early clue of chronic severe hyponatremia.
An 81-year-old woman was admitted after three days of altered mental status. Her complete blood count showed a markedly elevated mean corpuscular hemoglobin concentration (MCHC) of 369 g/L; the blood smear showed…
Ketamine and esketamine during breastfeeding: a systematic review of human pharmacokinetic, infant and lactation outcomes.
This systematic review synthesised human evidence on ketamine and esketamine transfer into breast milk, infant exposure and outcomes, and breastfeeding outcomes after postpartum exposure.
Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial.
This pre-specified analysis of the multicentre, randomised DECISION trial examined blinded withdrawal of long-term low-dose digoxin or placebo in patients with heart failure and reduced or mildly reduced ejection…
Effects of Sodium Bicarbonate Ringer's Solution versus Lactate Ringer's Solution on Emergence Time in Patients Undergoing Supratentorial Tumor Resection: A Randomized Controlled Trial.
This randomized controlled trial compared intraoperative sodium bicarbonate Ringer’s solution (BRS) with lactated Ringer’s solution (LRS) in patients undergoing elective supratentorial tumor resection.
Analysis of a case of immune-related pancreatitis induced by anti-PD-1 antibody therapy for gastric cancer: A case report.
An 82-year-old woman with metastatic gastric cancer developed mild epigastric pain and acid regurgitation, with elevated pancreatic enzymes, on the second day of her fourth cycle of nivolumab plus apatinib.
Metallic versus plastic stents for the management of biliary obstruction: A GRADE-assessed systematic review and meta-analysis.
This GRADE-assessed systematic review and meta-analysis compared metallic with plastic stents for benign or malignant biliary obstruction, including randomized and observational studies.
Giant cystic lymphangioma in the pancreatic tail-splenic hilum region managed by en bloc resection: A case report.
A 43-year-old woman presented with two days of persistent dull left upper abdominal pain and nonspecific inflammatory and mild hepatobiliary laboratory abnormalities.
Pediatric anti-GBM crescentic glomerulonephritis: partial renal recovery following plasmapheresis and mycophenolate mofetil.
A 14-year-old girl presented with acute edema and hypertension. Investigations showed hematuria, proteinuria, hypoalbuminemia, worsening renal function, and positive anti-GBM antibodies.
Histiocytoid melanoma presenting as lymphadenopathy and mimicking Rosai-Dorfman disease.
A patient presented with large, unilateral inguinal lymphadenopathy. Excisional biopsy showed expanded lymph-node sinuses containing large cells with abundant granular eosinophilic cytoplasm, eccentric nuclei, and…
Curcumin in ovarian cancer: mechanistic insights and translational potential.
This systematic review assessed curcumin and curcumin nanoformulations in preclinical ovarian cancer models, evaluating 21 studies.
Invasive interval breast cancer rates after digital breast tomosynthesis plus synthesised mammography versus digital mammography screening (TOSYMA): 24-month follow-up of the multicentre, open-label, randomised, controlled, superiority trial.
TOSYMA-2 was the 24-month follow-up of a multicentre, open-label, randomised superiority trial at 17 German screening sites.
Concurrent biliary atresia and intestinal atresia: a systematic review of clinical characteristics, pathogenesis, management, and outcomes.
This systematic review examined clinical features, management, and outcomes in patients with concurrent biliary atresia (BA) and intestinal atresia (IA), drawing on case reports, case series, and retrospective reviews.
Nursing-led predictive symptom management in oncology palliative care: Using laboratory indicators and clinical judgment to improve patient quality of life: A systematic review.
This systematic review examined nurse-led predictive symptom-management strategies in oncology palliative care, including the use of laboratory biomarkers alongside clinical judgment.
Near point-of-care nucleic acid amplification tests (NPOC-NAATs) using respiratory specimens for detection of pulmonary tuberculosis.
This Cochrane systematic review and meta-analysis assessed near point-of-care nucleic acid amplification testing for pulmonary tuberculosis in adults, adolescents, and children with presumptive disease.
Detection of MOG-IgG and MOG-IgA in Maternal Breast Milk and Infant Blood in MOGAD: A Case Report.
A mother with MOG antibody-associated disease had persistently elevated plasma MOG-IgG, with a transient decrease in early pregnancy.
A pedicled buccal fat pad for paranasal volume augmentation in orthognathic surgery: a case report.
A patient with a round face and maxillary hypoplasia underwent orthognathic surgery, but the maxilla could not be advanced as far as desired for dental and aesthetic reasons.
Sex differences in pharmacological treatment of heart failure: a meta-analysis of randomized trials.
This systematic review and meta-analysis examined sex differences in pharmacological treatment effects across randomized heart failure trials and whether women’s representation influenced estimated efficacy.
Attributable fraction of cardiac disease following radiotherapy among breast cancer survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed the relationship between mean heart dose (MHD) from radiotherapy and cardiac disease among breast cancer survivors.
A Giant Intra-Abdominal Plasmablastic Neoplasm Favoring Lymphoma Mimicking an Exacerbation of Severe Fistulizing Crohn's Disease: A Case Report.
A 44-year-old woman with severe fistulizing Crohn’s disease developed progressive systemic deterioration despite partial intestinal stabilization.
Regression of uremic tumoral calcinosis following the switch from cinacalcet to etelcalcetide in a hemodialysis patient without severe hyperphosphatemia.
A 46-year-old man receiving maintenance hemodialysis developed progressive peri-articular soft-tissue calcifications that became tumoral calcinosis (TC), involving both thighs and the left elbow and causing a left…
Oral microbiome alterations in individuals with type 1 diabetes: a systematic review.
This systematic review evaluated associations between glycemic control and oral microbial findings in people with type 1 diabetes (T1DM), distinguishing targeted tests from comprehensive microbiome profiling.
Measurement properties of pulmonary function measurement and patient-reported outcome measures in patients with multiple rib fracture without flail segment; validation study alongside the multicenter FixCon trial.
This multicenter validation study, conducted alongside a randomized controlled trial, assessed pulmonary function, pain, and health-related quality-of-life measures in 180 adults with multiple rib fractures without a…
Magnitude and Moderators of Depressive Symptom Improvement in Digital Placebo Arms: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined blinded randomised controlled trials using digital placebos as comparators and reporting PHQ-9 outcomes.
Fragility of randomized clinical trials comparing surgical approaches for inguinal hernia repair: a systematic review.
This systematic review assessed the fragility of dichotomous findings in randomized trials comparing inguinal hernia repair approaches.
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