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1999 articles

October 202624

Clinical ResearchOncology (Medical)Open access

Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.

This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…

Nat CommunOct 23, 2026Read summary
Case ReportPediatrics

Fosfomycin-induced liver injury in a 17-year-old patient: A case report.

A previously healthy 17-year-old male developed nausea, vomiting, fever, progressive epigastric pain, fatigue, and malaise.

Am J Health Syst PharmOct 23, 2026Read case
Clinical ResearchPediatricsOpen access

Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.

Eur J PediatrOct 23, 2026Read summary
Case ReportNephrologyOpen access

Anti-GBM/ANCA double-positive crescentic nephritis in an elderly patient presenting with heart failure-like symptoms: A case report.

A 74-year-old woman presented with progressive shortness of breath, nausea, and vomiting, initially raising concern for heart failure. Testing instead showed severe renal impairment (creatinine 1025.99 μmol/L).

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchEmergency Medicine

Jidesheng Snake Pills as Adjunctive Therapy for Snakebite: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis assessed randomized evidence for Jidesheng Snake Pills as adjunctive treatment for snakebite. Five unique trials involving 458 participants were included.

J Vis ExpOct 23, 2026Read summary
Case ReportNeurology

Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.

A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.

J Peripher Nerv SystOct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Case ReportUrology

Robotic Totally Intracorporeal Bilateral Boari Flap Reconstruction for Complex Bilateral Ureteral Strictures: A Step-by-Step Technique.

A 42-year-old woman with complex bilateral mid- and distal ureteral strictures underwent robotic, totally intracorporeal bilateral Boari flap reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportUrology

Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.

A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.

Int Braz J UrolOct 23, 2026Read case
Case ReportInfectious DiseasesOpen access

Pulmonary infection caused by Nocardia cyriacigeorgica and influenza A virus coinfection in an immunocompetent patient: A case report.

A 60-year-old immunocompetent man without reported underlying pulmonary disease presented with recurrent cough and sputum production over 5 months, worsening respiratory symptoms, and recent fever.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportOphthalmologyOpen access

Isolated necrotizing scleritis revealing silent pulmonary granulomatosis with polyangiitis: A case report of rare diagnostic clue.

A 31-year-old man with recurrent unilateral necrotizing anterior scleritis that resisted corticosteroids and immunosuppressants had no systemic symptoms.

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportPediatrics

Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.

Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.

Am J Case RepOct 22, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Platelet-rich plasma for knee osteoarthritis: a systematic review and meta-analysis of structural outcomes.

This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.

Arch Orthop Trauma SurgOct 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Drug-coated balloons in coronary disease: meta-analysis comparing sirolimus- and paclitaxel-coated technologies.

This systematic review and meta-analysis compared sirolimus-coated balloons (SCBs) with paclitaxel-coated balloons (PCBs) for coronary interventions.

BMC Cardiovasc DisordOct 22, 2026Read summary
Clinical ResearchPediatrics

Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.

This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.

Quintessence IntOct 22, 2026Read summary
Case ReportInfectious Diseases

Simple Site, Serious Sequelae: Septic Emboli from a Peripheral Cannula.

A young woman developed right arm pain and pleuritic chest pain after a recent hospitalisation, with marked inflammation (CRP 296 mg/L, WCC 13.7 ×10⁹/L).

Ir Med JOct 22, 2026Read case
Clinical ResearchNephrology

Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.

This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.

J NephrolOct 22, 2026Read summary
Case ReportRheumatologyOpen access

Effectiveness of tocilizumab monotherapy for IgG4-related disease-like features caused by idiopathic multicentric Castleman's disease: a case-based review.

A 68-year-old woman presented with dyspnea associated with a recurrent laryngeal tumor, pulmonary consolidation, mediastinal and axillary lymphadenopathy, sclerosing mesenteritis, and retroperitoneal fibrosis.

Rheumatol IntOct 22, 2026Read case
Clinical ResearchHematologyOpen access

Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.

The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.

Blood Cancer JOct 22, 2026Read summary
Case ReportObstetrics & Gynecology

A Cluster of Anencephaly Cases: The Potential Preventative Role of Folic Acid Fortification.

Over two weeks, a peripheral maternity unit identified four fetuses with severely abnormal cranial views on ultrasound; three cases were described.

Ir Med JOct 22, 2026Read case
Case ReportNeurosurgeryOpen access

Unexpected Right-Sided Nerve Root Variant During L4-L5 Microdiscectomy and Decompression: A Case Report Highlighting Diagnostic and Intraoperative Challenges.

A 45-year-old woman presented with predominantly right-sided leg numbness and paresthesia, radiating pain, and preserved strength.

Int Med Case Rep JOct 22, 2026Read case
Clinical ResearchPulmonology

Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.

Med Sci MonitOct 22, 2026Read summary

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