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2000 articles

October 202624

Case ReportInfectious DiseasesOpen access

Blackwater Fever Complicated by Severe Acute Kidney Injury and a Therapeutic Dilemma: A Case Report from Niger.

A 50-year-old woman with persistent Plasmodium falciparum infection and repeated antimalarial treatment, including artesunate, presented with fever, jaundice, and severe acute kidney injury (serum creatinine 1104.1…

Int Med Case Rep JOct 3, 2026Read case
Case ReportOncology (Medical)Open access

Complete Regression of 11 Hepatic Metastases in Metastatic Pancreatic Adenosquamous Carcinoma and the Role of GPT in Patient Navigation.

A 65-year-old man with resected pancreatic adenosquamous carcinoma (pT3 pN2, R0) had 11 liver lesions interpreted as metastases on MRI.

Int Med Case Rep JOct 3, 2026Read case
Clinical ResearchPediatrics

Impact of digital health interventions in improving pediatric immunization coverage and timeliness in low- and middle-income countries: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomized controlled trials of digital interventions to improve pediatric vaccination outcomes in low- and middle-income countries.

VaccineOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparison of Molecular Methods With Culture for Identifying Microbial Etiology in Pediatric Empyema Thoracis: A Systematic Review of Diagnostic Test Accuracy.

This systematic review evaluated the diagnostic accuracy of molecular methods versus culture for identifying microbial etiology in pediatric empyema thoracis.

Indian PediatrOct 2, 2026Read summary
Clinical ResearchFamily Medicine

Implementation of Communication Disability Documentation and Accommodations in Primary Care: A Pragmatic Type III Hybrid Implementation-Effectiveness Trial Protocol.

This article describes the protocol for the DECA study, a pragmatic Type III hybrid implementation-effectiveness trial of communication disability (CD) documentation and accommodation processes in primary care.

J Speech Lang Hear ResOct 2, 2026Read summary
Clinical ResearchPsychiatryOpen access

A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.

The REPICAL study evaluated a digital stepped-care program aimed at reducing anxiety and depressive symptoms among long-term care workers (LTCWs) in Catalonia, Spain.

Depress AnxietyOct 2, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.

Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).

Hum MutatOct 2, 2026Read summary
Clinical ResearchEndocrinology

Native collagen matrix plus PHMB antimicrobial in hard-to-heal diabetic foot ulcers: results from the PREPARE randomised controlled trial.

The PREPARE prospective, multicentre randomised controlled trial compared purified native type 1 collagen extracellular matrix plus polyhexamethylene biguanide (PCMP) with standard care (SoC) alone in patients with…

J Wound CareOct 2, 2026Read summary
Case ReportPediatrics

Primary Surgical Resection of Localized Cervical Kaposiform Hemangioendothelioma in a Neonate: A Potentially Curative Strategy in Selected Patients.

A term female neonate had a 4 × 4 cm cervical mass at birth. Imaging showed a well-circumscribed, highly vascular lesion without infiltration or compression of vital structures; no coagulopathy was detected.

J Pediatr Hematol OncolOct 2, 2026Read case
Clinical ResearchOncology (Medical)

Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.

The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…

BrachytherapyOct 2, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Non-Ischemic Cerebral Enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a systematic review with case-level synthesis.

This PROSPERO-registered systematic review synthesized reports of delayed non-ischemic cerebral enhancing (NICE) lesions after flow-diverter treatment of intracranial aneurysms; heterogeneity precluded meta-analysis.

BMC NeurolOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Postnatal interventions to support newborn survival: updates for the Lives Saved Tool.

This systematic review evaluated postnatal interventions aimed at reducing neonatal mortality, particularly in low- and middle-income countries.

J Glob HealthOct 2, 2026Read summary
Case ReportGastroenterologyOpen access

Markedly Elevated CA 19-9 in Type I Mirizzi Syndrome in the Absence of Malignancy: A Case Report.

A 50-year-old man presented with acute obstructive jaundice, fever, and right upper quadrant pain; serum CA 19-9 was 1000 U/mL.

Int Med Case Rep JOct 2, 2026Read case
Case ReportMedical Genetics

Hereditary Neuropathies.

This article describes the clinical features, genetic causes, and diagnostic strategies of inherited peripheral neuropathies, and highlights how recent developments are reshaping the management of these disorders.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Paraproteinemic Neuropathies.

Paraproteinemic neuropathies present with a myriad of phenotypes and associated underlying plasma cell dyscrasias. This article provides a phenotype-driven approach to the evaluation of paraproteinemic neuropathies…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportPediatrics

Spinal Muscular Atrophy.

This article reviews the history, epidemiology, genetics, clinical presentation, multidisciplinary management, and established and emerging therapies for patients with spinal muscular atrophy.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Inflammatory and Autoimmune Axonal Neuropathies.

This article outlines the clinical patterns, diagnostic strategies, and treatment principles for patients with inflammatory and autoimmune axonal neuropathies.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Nutritional and Toxic Neuropathies.

This article reviews the etiologies, clinical presentations, and management of nutritional and toxic neuropathies.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Diabetic Neuropathies.

This article provides an update on the biological mechanisms and risk factors for the varied manifestations of diabetes-associated nerve injury, and reviews current diagnostic and treatment approaches.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

This article describes the cardinal clinical, electrophysiologic, and supportive features of typical CIDP and its variants, how to review and apply CIDP diagnostic criteria, objective measures that can be used in…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Amyotrophic Lateral Sclerosis.

This article describes the nerve loss underlying amyotrophic lateral sclerosis, its clinical manifestations, examination findings leading to the diagnosis, the expanding role of genetics, and available treatment and…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Amyloid Neuropathies.

This article reviews the pathophysiology, epidemiology, and clinical features of amyloid neuropathies, with a focus on light chain (AL) amyloidosis and hereditary amyloidogenic transthyretin (ATTRv) amyloidosis, and…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Wellness and Career Sustainability in Neurology.

This article reviews drivers of well-being in neurology, using the practice of neuromuscular neurology as an example and high-yield interventions to enhance professional fulfillment.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Small Fiber Neuropathy.

Small fiber neuropathy is a common disorder; however, its diagnosis and treatment can be challenging. This article outlines the pain pathways involved in small fiber neuropathy and provides an overview of its various…

Continuum (Minneap Minn)Oct 2, 2026Read case

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