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2000 articles
October 202624
The association between e-cigarette use and dyslipidemia: A systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis examined observational evidence on exclusive e-cigarette use and blood lipids in adults. Seven studies from four countries included 25,690 participants.
Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .
This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.
The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial.
This single-centre, prospective, double-blind randomised controlled trial compared a lidocaine ice popsicle containing simethicone and N-acetylcysteine (NAC) with a conventional lidocaine popsicle in 374 adults…
Association of Screen Time With Physical and Mental Health in University Students: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined screen-time duration and physical and mental health outcomes in university students aged 17 years or older.
From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.
This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.
Beyond denial: A case report illustrating the complexity of disengagement in advanced cancer care.
A woman in her forties from Africa with advanced metastatic gastric cancer declined prognostic discussions, did not want her family informed, and avoided opioid analgesia.
Intracardiac thrombus and multiple venous thromboses revealing focal segmental glomerulosclerosis.
A 51-year-old woman presented with two weeks of lower-limb edema and hematuria. Imaging showed lower-extremity deep vein thrombosis, partial left renal vein thrombosis, and a 23 × 20 mm left ventricular thrombus.
Previously Unrecognized Distinct Laryngeal Lesions During Lazertinib Therapy in EGFR-Mutated NSCLC: A Case Series.
Four patients with non-small cell lung cancer developed new voice changes or a globus sensation while receiving lazertinib-based therapy.
Crisis Interventions for Children and Adolescents with Depression and Suicidality: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined crisis services for children and adolescents experiencing acute mental health crises, including severe depression, suicidal ideation, self-harm, and suicidal behaviour.
"What a beautiful gift, life": Dignity therapy and the making of a legacy in a patient with grade 4 glioblastoma.
A man in his mid-40s with grade 4 glioblastoma of the corpus callosum received psycho-oncological support from diagnosis, with parallel support for his caregiver.
A closer look at LATE: a Case Report on a subtly evolving neurodegenerative disorder.
A 71-year-old presented with isolated episodic memory impairment, preserved global cognition, and intact daily function. Initial cerebrospinal fluid (CSF) Alzheimer’s disease (AD) biomarkers were negative, and 18F-FDG…
Non-recurrent laryngeal nerve with dual branch pattern and merging: a rare anatomical variant encountered during right hemithyroidectomy.
A woman in her 50s underwent right hemithyroidectomy for a benign compressive multinodular goitre. The recurrent laryngeal nerve was not found in its expected tracheo-oesophageal groove position.
Imaging Features and Prognosis of Anti‑Sez6l2 Encephalitis: A Longitudinal Cohort Study and Literature Review.
This longitudinal cohort study and systematic review examined clinical features, multimodal imaging, and treatment response in anti-Sez6l2 encephalitis.
Outdoor risky play and health-related outcomes in children aged 3-12 years: A mixed-methods systematic review.
This mixed-methods systematic review synthesised evidence on outdoor risky play and health outcomes in children aged 3–12 years. It included 74 studies: 48 quantitative, 19 qualitative and 7 mixed-methods.
Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.
This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.
Dose-Response Effects of Exercise Training on Circulating Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-analysis of Randomised Controlled Trials.
This systematic review and meta-analysis pooled randomised controlled trials comparing chronic exercise with non-exercising controls to assess circulating brain-derived neurotrophic factor (BDNF).
Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.
This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.
Adjunctive topical mitomycin C during endoscopic dilation for pediatric caustic esophageal stricture: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis assessed topical mitomycin C (MMC) added to endoscopic dilation for caustic esophageal stricture in children.
Tricuspid Chordae Tendineae Rupture Detected After Repair of a Delayed Traumatic Left Ventricular Aneurysm: A Case Report.
After a fall from a height, a patient presented 54 days later with rupture of a posterior left ventricular aneurysm. Venoarterial extracorporeal membrane oxygenation provided circulatory support before surgical aneurysm…
A novel PGAP1 splice-site variant expanding the clinical and molecular spectrum of GPI-anchor disorders.
A patient with neurodevelopmental impairment was found to carry a novel homozygous PGAP1 splice-site variant, NM_024989.4.1173 + 1G > A.
Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy versus standard of care for locally advanced rectal cancer (UNION): a prespecified interim analysis of a multicentre, open-label, randomised, phase 3 trial.
UNION was a multicentre, open-label, randomised phase 3 trial at nine hospitals in China comparing neoadjuvant short-course radiotherapy followed by camrelizumab plus CAPOX with long-course chemoradiotherapy followed by…
Reduced-dose alternate-day oral iron supplementation in women with iron deficiency: a randomized controlled trial.
This 42-day, randomized, parallel-group active-controlled trial compared two oral iron regimens in 66 women aged 18–50 years with iron deficiency (serum ferritin < 30 ng/mL).
Extensive Arterial Thrombosis Complicating Acute Pancreatitis: A Case Report and Literature Review.
A 61-year-old man with chronic pancreatitis developed acute interstitial edematous pancreatitis. Four weeks after presentation, persistent dyspepsia prompted contrast-enhanced CT, which showed pancreatic pseudocysts and…
Fishbone-Induced Gastrointestinal Perforation: A 21-Case Series from Vietnam.
This retrospective series included 21 patients treated for fishbone-induced gastrointestinal perforation at a tertiary hospital in southern Vietnam.
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