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2000 articles

October 202624

Case ReportOncology (Medical)

Previously Unrecognized Distinct Laryngeal Lesions During Lazertinib Therapy in EGFR-Mutated NSCLC: A Case Series.

Four patients with non-small cell lung cancer developed new voice changes or a globus sensation while receiving lazertinib-based therapy.

J Korean Med SciOct 26, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Does the "switch the plane" strategy improve outcomes? Anterior vs. posterior repair for recurrence after prior inguinal hernia repair: a systematic review and meta-analysis.

This systematic review and meta-analysis examined outcomes of recurrent unilateral inguinal hernia repair by operative plane, including comparative studies of posterior versus repeat anterior repair after prior anterior…

HerniaOct 26, 2026Read summary
Clinical ResearchPsychiatryOpen access

An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.

This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…

Personal Ment HealthOct 26, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Are intervention effects on fruit and vegetable intake maintained after 48 months of follow-up? A randomised controlled community trial.

This randomised controlled community trial assessed whether increases in fruit and vegetable (FV) intake after a 7-month transtheoretical model-based intervention were maintained among users of a Brazilian primary…

Public Health NutrOct 26, 2026Read summary
Clinical ResearchCardiology

Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.

This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.

Eur Heart JOct 26, 2026Read summary
Clinical ResearchGastroenterology

The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial.

This single-centre, prospective, double-blind randomised controlled trial compared a lidocaine ice popsicle containing simethicone and N-acetylcysteine (NAC) with a conventional lidocaine popsicle in 374 adults…

PLoS OneOct 26, 2026Read summary
Clinical ResearchPediatrics

Outdoor risky play and health-related outcomes in children aged 3-12 years: A mixed-methods systematic review.

This mixed-methods systematic review synthesised evidence on outdoor risky play and health outcomes in children aged 3–12 years. It included 74 studies: 48 quantitative, 19 qualitative and 7 mixed-methods.

PLoS OneOct 26, 2026Read summary
Case ReportPediatricsOpen access

Long-term consequences in RAS blocker-induced fetopathy with multiorgan impairments.

A girl with fetopathy after maternal exposure to a renin–angiotensin system blocker was followed for 10 years. She had severe short stature and persistent mild developmental delay; cranioplasty at 1 year revealed right…

CEN Case RepOct 26, 2026Read case
Clinical ResearchOrthopedic Surgery

Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .

This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchPsychiatry

Family Resilience and Coping in Disasters, Pandemics, and Large-Scale Crises: A Systematic Review.

This systematic review synthesized peer-reviewed research on family resilience and coping during disasters, pandemics, and sustained adversity.

Disaster Med Public Health PrepOct 26, 2026Read summary
Clinical ResearchPsychiatry

Lithium in the Prevention of Postpartum Recurrence of Mood Disorders: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed postpartum mood-disorder recurrence among women with bipolar I or II disorder, comparing those who received prophylactic lithium with those who did not.

J Clin PsychiatryOct 26, 2026Read summary
Clinical ResearchCardiology

Safety and Effectiveness of a Novel Laser-Based Intravascular Lithotripsy System for Coronary Calcium: FRACTURE Study.

FRACTURE was a prospective, multicenter, single-arm clinical trial evaluating a laser- and optic-based quad-emitter intravascular lithotripsy system in patients with severely calcified de novo coronary lesions.

JACC Cardiovasc IntervOct 26, 2026Read summary
Clinical ResearchPsychiatryOpen access

Crisis Interventions for Children and Adolescents with Depression and Suicidality: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined crisis services for children and adolescents experiencing acute mental health crises, including severe depression, suicidal ideation, self-harm, and suicidal behaviour.

Curr Psychiatry RepOct 26, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Evaluating gain and loss-framed mobile messaging to improve maternal health service uptake: A cluster randomized controlled trial in Jimma, Ethiopia.

This three-arm cluster-randomized controlled trial assessed whether gain- or loss-framed SMS messaging improved maternal health service use among 588 pregnant women in Jimma Zone, Ethiopia.

PLoS OneOct 26, 2026Read summary
Clinical ResearchPulmonology

Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.

This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.

Rev Med VirolOct 26, 2026Read summary
Clinical ResearchNeurology

From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.

This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchEndocrinology

Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .

This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Exposure to antidepressant and antipsychotic medicines in pregnant women and risk of gestational diabetes: a systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis pooled observational studies of gestational diabetes mellitus (GDM) among pregnant women exposed to antidepressants or antipsychotics.

Arch Womens Ment HealthOct 26, 2026Read summary
Clinical ResearchPulmonologyOpen access

Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.

This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.

Eur J Sport SciOct 26, 2026Read summary
Case ReportNephrologyOpen access

Intracardiac thrombus and multiple venous thromboses revealing focal segmental glomerulosclerosis.

A 51-year-old woman presented with two weeks of lower-limb edema and hematuria. Imaging showed lower-extremity deep vein thrombosis, partial left renal vein thrombosis, and a 23 × 20 mm left ventricular thrombus.

CEN Case RepOct 26, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

The association between e-cigarette use and dyslipidemia: A systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis examined observational evidence on exclusive e-cigarette use and blood lipids in adults. Seven studies from four countries included 25,690 participants.

PLoS OneOct 26, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Sialadenopapillary Ductal Tumor: Case Series and Review of the Literature.

The authors describe three patients with sialadenopapillary ductal tumors, a rare neoplasm of likely minor salivary gland origin characterized by prominent submucosal ductal proliferation and multilayered cystic…

Head Neck PatholOct 26, 2026Read case
Case ReportUrology

Bilateral Xanthogranulomatous Pyelonephritis in a Patient With Spina Bifida and Neurogenic Bladder: A Case Report.

A 30-year-old man with spina bifida and neurogenic bladder managed by intermittent catheterization presented with respiratory distress, profound anemia, and declining function.

Am J Case RepOct 26, 2026Read case
Clinical ResearchPediatrics

Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.

This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.

Scand J Med Sci SportsOct 26, 2026Read summary

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