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2000 articles

October 202624

Case ReportOphthalmologyOpen access

Trigeminal sensory neuropathy developing as a late complication after the treatment of surgically induced necrotizing scleritis following pterygium surgery: a case report and literature review.

A 31-year-old woman developed right-eye irritation, reduced vision, and photophobia after bilateral pterygium surgery. Examination showed melting of the conjunctival autograft with exposed sclera and a visible choroidal…

BMC OphthalmolOct 8, 2026Read case
Clinical ResearchHematology

Anticoagulation with the mechanistically distinct FXI/FXIa antibodies amrecibart (REGN9933A2) and cenvacibart (REGN7508Cat).

This Phase I randomised controlled trial programme evaluated two mechanistically distinct factor XI/FXIa monoclonal antibodies as potential anticoagulants, using in vitro assays, nonhuman primates and healthy…

BloodOct 8, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Efficacy and safety of endovascular coiling compared to microsurgical clipping in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis of randomized trials.

This systematic review and meta-analysis of six randomised trials, including up to 3044 patients with ruptured intracranial aneurysms, compared endovascular coiling with microsurgical clipping.

J NeurolOct 8, 2026Read summary
Case ReportNeurologyOpen access

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.

A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).

J Med Case RepOct 7, 2026Read case
Clinical ResearchRheumatology

Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.

This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…

VaccineOct 7, 2026Read summary
Case ReportAnesthesiologyOpen access

Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.

Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…

Drug Des Devel TherOct 7, 2026Read case
Clinical ResearchInfectious Diseases

A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults.

This randomised phase 1/2 dose-ranging study evaluated the safety, reactogenicity, and immunogenicity of mRNA-1018 pandemic influenza vaccine candidates in healthy adults.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial.

This randomized, double-blind, active-comparator phase 2 trial compared the safety and immunogenicity of single-dose quadrivalent dengue vaccines V181 and Butantan-DV in healthy adults in Brazil.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Fosfomycin as Oral Transition Therapy Versus Continued Intravenous β-Lactams for Complicated Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase-Producing Enterobacterales: A Multicenter, Open-Label, Randomized Controlled Trial.

This multicenter, open-label randomized noninferiority trial compared oral fosfomycin transition therapy with continued intravenous carbapenem or β-lactam/β-lactamase inhibitor therapy in hospitalized adults with…

Clin Infect DisOct 7, 2026Read summary
Case ReportHematology

Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.

An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.

Anticancer DrugsOct 7, 2026Read case
Case ReportOncology (Medical)

Case report: successful use of repotrectinib in a ROS1 fusion-positive lung adenocarcinoma patient with severe renal insufficiency and prior tyrosine kinase inhibitor treatment failure.

A 69-year-old woman with advanced lung adenocarcinoma harboring an SDC4–ROS1 fusion had bilateral pulmonary lesions, mediastinal lymphadenopathy, and pleural effusions.

Anticancer DrugsOct 7, 2026Read case
Case ReportNeurologyOpen access

Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.

The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.

Int Med Case Rep JOct 7, 2026Read case
Case ReportPlastic Surgery

Capsulectomy at Explant: Rethinking Spinal Cord Stimulator Infected Generator Pocket Management in the Immunocompromised-A Case Series.

Two immunocompromised women with spinal cord stimulator (SCS) infections underwent explantation and capsulectomy. The first patient, with ulcerative colitis and psoriatic arthritis, developed granulation tissue and was…

Pain PractOct 7, 2026Read case
Case ReportPediatrics

Recurrent Ovarian Torsion Despite Previous Oophoropexy in a 9-Year-Old Prepubertal Girl: A Pediatric Emergency Department Perspective.

A 9-year-old prepubertal girl with prior left ovarian torsion treated by laparoscopic detorsion and oophoropexy presented with severe intermittent left-sided abdominal pain and vomiting.

Am J Case RepOct 7, 2026Read case
Clinical ResearchInfectious Diseases

Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.

This analysis of a cluster-randomized trial in South Africa examined whether household multidimensional poverty was associated with the reach of household contact tracing (HHCT) for tuberculosis.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchAnesthesiology

Daily sedation interruption versus no daily sedation interruption for critically ill adults and children requiring invasive mechanical ventilation.

This updated Cochrane systematic review and meta-analysis assessed daily sedation interruption (DSI) versus sedation strategies without interruption in critically ill adults and children receiving invasive mechanical…

Cochrane Database Syst RevOct 7, 2026Read summary
Clinical ResearchOrthopedic Surgery

Costs and health-related quality of life of non-operative and surgical treatment modalities for displaced distal radius fractures: a comprehensive overview based on the CAST study.

This cost and health-related quality-of-life analysis used data from the multicenter cluster-randomized CAST trial of adults with displaced distal radius fractures.

Eur J Trauma Emerg SurgOct 7, 2026Read summary
Case ReportPulmonologyOpen access

Clinical features of cough syncope: a systematic review.

The article presents five cases of cough syncope and reviews published clinical characteristics, comprising 60 patients with a mean age of 56 ± 15 years; 91% were male.

Neurol SciOct 7, 2026Read case
Clinical ResearchGastroenterologyOpen access

Co-supplementation of zinc and probiotic on oxidative stress markers and sleep quality index in irritable bowel syndrome patients: a double-blind randomized controlled trial.

This parallel, double-blind randomised controlled trial assessed zinc alone and zinc plus probiotics in 84 people with irritable bowel syndrome over 90 days, comparing both with placebo.

Eur J NutrOct 7, 2026Read summary
Clinical ResearchPsychiatryOpen access

Prediction models for postpartum post-traumatic stress disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed multivariable models predicting post-traumatic stress disorder within 12 months after childbirth.

Arch Womens Ment HealthOct 7, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comparison of perioperative outcomes for da Vinci robotic-assisted, laparoscopic and open surgery in oncologic procedures: a systematic literature review and meta-analysis of evidence from China.

This systematic review and meta-analysis pooled 116 comparative studies published from 2010 to 2024 on da Vinci robot-assisted surgery (dV-RAS) versus laparoscopic/video-assisted thoracoscopic surgery (LAP/VATS) or open…

J Robot SurgOct 7, 2026Read summary
Clinical ResearchNeurologyOpen access

Healthcare costs and burden of myasthenia gravis for patients and society: a systematic review.

This systematic review examined healthcare and societal costs associated with myasthenia gravis (MG), including 44 studies selected from 1,374 records.

J NeurolOct 7, 2026Read summary
Case ReportDermatology

A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).

A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.

Am J Case RepOct 7, 2026Read case
Clinical ResearchEndocrinologyOpen access

Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.

This systematic review synthesised U.S. evidence on disparities in prescribing and initiation of GLP-1 receptor agonists and SGLT2 inhibitors, and proposed an equity-first framework for cardiovascular-kidney-metabolic…

Curr Cardiol RepOct 7, 2026Read summary

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