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2000 articles

October 202624

Clinical ResearchInfectious Diseases

Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted Staphylococcus aureus Vaccine in Adults With Recent Skin and Soft Tissue Infections: An Observer-Blind, Randomized, Placebo-Controlled, Multinational Phase 1/2 Trial.

This observer-blind, randomized, placebo-controlled phase 1/2 trial evaluated a five-antigen Staphylococcus aureus vaccine with AS01E adjuvant in adults, including 194 participants aged 18–64 years with a recent S.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchUrology

Digital health technologies for the prevention and management of urinary tract infections in menopausal women: A systematic review.

This systematic review synthesised evidence on digital technologies for preventing or managing urinary tract infections in menopausal women.

MaturitasOct 7, 2026Read summary
Case ReportCardiology

Anterior ST-Segment Elevation Myocardial Infarction With Coronary Thrombosis in a Young Man with Newly Diagnosed HIV Infection and Pneumocystis jirovecii Pneumonia.

A 36-year-old man with newly diagnosed, severely immunosuppressive HIV infection and Pneumocystis jirovecii pneumonia developed an acute anterior ST-segment elevation myocardial infarction 25 days after starting…

Turk Kardiyol Dern ArsOct 7, 2026Read case
Clinical ResearchUrology

MRI-derived radiomics for prostate cancer active surveillance: a systematic review.

This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Systematic Review and Meta-Analyses of Time-Use, Productivity, and Labor Outcomes Among Unpaid Cancer Caregivers.

This systematic review and meta-analysis pooled evidence on time use and labor outcomes among unpaid caregivers of adults with cancer.

JCO Glob OncolOct 7, 2026Read summary
Clinical ResearchGeriatrics

Immunogenicity and Safety of Co-administration of Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine With 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: A Randomized, Non-inferiority Trial.

This phase III, open-label, randomized non-inferiority trial compared concomitant versus one-month-apart administration of adjuvanted RSV prefusion F protein vaccine (RSVPreF3) and 20-valent pneumococcal conjugate…

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Immunogenicity and Safety of the Adjuvanted Respiratory Syncytial Virus Prefusion F Protein-Based Vaccine When Co-administered With the Adjuvanted Recombinant Herpes Zoster Subunit Vaccine in Adults ≥ 50 Years of Age.

This phase III, open-label, randomised trial compared co-administration of adjuvanted RSVPreF3 and recombinant zoster vaccine (RZV) with administration one month apart in adults aged ≥50 years.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchPsychiatryOpen access

Anxiety and Depression in Athletes of Different Levels Without Current Injury: A Systematic Review With Meta-Analyses.

This systematic review and random-effects meta-analysis examined anxiety and depression in athletes across competitive levels, including those without current injury.

J Athl TrainOct 7, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.

Ren FailOct 6, 2026Read summary
Clinical ResearchPulmonology

'Life has become a lot easier'-the acceptability of the treatable traits clinic experience to people with bronchiectasis.

This exploratory qualitative study examined how adults with bronchiectasis experienced a regional Australian outpatient clinic using a treatable-traits approach.

Ann MedOct 6, 2026Read summary
Clinical ResearchPulmonologyOpen access

Neuromuscular, Balance, and Gait Factors Associated with Falls and Fall-Related Outcomes in Individuals with COPD: A Systematic Review.

This systematic review examined associations between muscle strength, balance, gait and falls or fall-related outcomes in people with COPD. It included 25 original studies involving 1295 participants.

Int J Chron Obstruct Pulmon DisOct 6, 2026Read summary
Case ReportPediatricsOpen access

Rupture of Left Ventricular Aneurysm in Infant: Case Report.

A preterm infant hospitalized from birth with necrotizing enterocolitis, later complicated by ascending-colon narrowing requiring surgery, had persistent infections with Staphylococcus haemolyticus and then…

Int Med Case Rep JOct 6, 2026Read case
Case ReportEndocrinologyOpen access

Severe Euglycemic Diabetic Ketoacidosis After Semaglutide-Associated Poor Intake Despite Empagliflozin Discontinuation: A Case Report.

A 68-year-old woman with long-standing type 2 diabetes developed several weeks of nausea, intermittent vomiting and diarrhea, and minimal oral intake after starting semaglutide.

Int Med Case Rep JOct 6, 2026Read case
Clinical ResearchHematologyOpen access

Infection burden in mismatched unrelated donor hematopoietic cell transplantation: results from the ACCESS trial.

The ACCESS trial evaluated infection burden in 268 adult patients undergoing HLA-mismatched unrelated donor hematopoietic cell transplantation (HCT) with posttransplant cyclophosphamide (PTCy) for graft-versus-host…

Blood AdvOct 6, 2026Read summary
Clinical ResearchCardiology

Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.

This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.

Clin Physiol Funct ImagingOct 6, 2026Read summary
Clinical ResearchNephrology

Efficacy and safety of roxadustat for the treatment of renal anemia in patients undergoing peritoneal dialysis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of roxadustat for treating renal anemia in patients undergoing peritoneal dialysis.

Ren FailOct 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.

Neurosci Biobehav RevOct 6, 2026Read summary
Clinical ResearchPsychiatry

Cannabis use and subsequent onset of manic symptoms and bipolar disorder: A systematic review and meta-analysis.

This registered systematic review and meta-analysis examined longitudinal observational studies of people without prior bipolar disorder, comparing those exposed and unexposed to cannabis.

J Affect DisordOct 6, 2026Read summary
Clinical ResearchPsychiatry

Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.

This systematic review and meta-analysis pooled randomised controlled trials of supervised exercise in adults receiving antipsychotic medication for psychotic disorders.

J Affect DisordOct 6, 2026Read summary
Clinical ResearchPsychiatry

Brief social contact videos to promote treatment seeking among young adults with depressive symptoms: Intention change, suicidal ideation, and treatment use in a randomized controlled trial.

This randomized controlled trial tested whether brief social contact videos featuring personal recovery stories increased help-seeking and treatment use among 1,545 young adults aged 18–25 years with depressive…

J Affect DisordOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity.

This randomized controlled trial compared frequent short walking bouts with one continuous bout in 30 adults with overweight or obesity.

Obesity (Silver Spring)Oct 6, 2026Read summary
Clinical ResearchGeriatrics

The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity.

This randomized controlled trial compared a weight-maintaining very low-carbohydrate diet (VLCD) with a low-fat diet (LFD) over 8 weeks in adults aged 60 years or older with obesity.

Obesity (Silver Spring)Oct 6, 2026Read summary
Clinical ResearchPediatricsOpen access

Iron or Multiple Micronutrient Powder Supplements With Malaria Chemoprevention in Rural Malawian Children: The IRMA Randomized Clinical Trial.

This randomized clinical trial evaluated the effects of iron supplements combined with malaria chemoprevention on cognitive outcomes in 6-month-old infants in rural Malawi.

JAMAOct 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

This individual participant data meta-analysis examined amyloid PET scans from 49,227 participants across 53 studies to establish Centiloid positivity cutoffs for Alzheimer disease diagnosis.

JAMAOct 6, 2026Read summary

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