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2000 articles

October 202624

Case ReportOrthopedic SurgeryOpen access

Integrated tendon repair and staged skin grafting for a severe forearm degloving injury: A case report from a low-resource setting.

A 21-year-old right-handed man presented two hours after a road traffic collision with extensive degloving of the right forearm, wrist, and dorsal thumb.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchInfectious Diseases

Evaluation of the Achievement of a Pharmacodynamic Target of Piperacillin-Tazobactam for the Population With Obesity: An Open Randomized Controlled Feasibility Study (TAZO-OBESITY Trial).

The open-label randomized feasibility trial TAZO-OBESITY compared standard with prolonged piperacillin-tazobactam infusions in patients with obesity (BMI ≥30 kg/m²).

Fundam Clin PharmacolOct 23, 2026Read summary
Clinical ResearchPsychiatry

Psychoeducation for posttraumatic stress disorder in adults: a systematic review of formats and delivery approaches.

This systematic review synthesized randomized controlled trials of psychoeducation for adults with PTSD, including interventions delivered alone or as a primary component.

Eur J PsychotraumatolOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Case ReportUrology

Robotic Totally Intracorporeal Bilateral Boari Flap Reconstruction for Complex Bilateral Ureteral Strictures: A Step-by-Step Technique.

A 42-year-old woman with complex bilateral mid- and distal ureteral strictures underwent robotic, totally intracorporeal bilateral Boari flap reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportOphthalmologyOpen access

Central retinal artery occlusion preceding hemispheric ischemic stroke treated with mechanical thrombectomy: A case report.

A 52-year-old man with dilated cardiomyopathy developed sudden, painless right-eye vision loss. Ophthalmologic examination and fluorescein angiography supported central retinal artery occlusion (CRAO).

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportOrthopedic SurgeryOpen access

A case report of pulmonary embolism following endoscopic cervical discectomy in an elderly patient with cervical disc herniation.

A 65-year-old woman with cervical disc herniation, right arm pain, and multiple comorbidities underwent posterior percutaneous endoscopic cervical discectomy after conservative treatment failed.

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportUrology

Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.

A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportMedical GeneticsOpen access

Delayed diagnosis of MEN1 after kidney transplantation: unrecognized pre-transplant features and implications for clinical practice.

A 68-year-old man with end-stage renal disease underwent living-donor kidney transplantation and had persistent hypercalcemia afterward.

CEN Case RepOct 23, 2026Read case
Clinical ResearchEndocrinology

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…

PLoS OneOct 23, 2026Read summary
Clinical ResearchPediatricsOpen access

Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.

Eur J PediatrOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.

Support Care CancerOct 23, 2026Read summary
Case ReportPsychiatry

Psychopathological and neuropsychological sequelae in children victimised by intimate partner violence: a clinical case series.

A clinical case series assessed four children aged 5–9 with documented exposure to intimate partner violence, including witnessing violence and, in some cases, direct abuse.

Eur J PsychotraumatolOct 23, 2026Read case
Case ReportOncology (Medical)Open access

Successful treatment with BrECADD in a patient with Dubin-Johnson syndrome and classic Hodgkin lymphoma: a case report.

A 26-year-old man with advanced-stage classic Hodgkin lymphoma also had Dubin–Johnson syndrome (DJS) associated with a homozygous ABCC2 variant, c.2291G>A (p.Gly764Asp).

Cancer Chemother PharmacolOct 23, 2026Read case
Case ReportOphthalmology

Anatomopathological Aspects and Clinical Correlation of Conjunctival Bleb Fibrosis Following Encapsulation of a Biodegradable Collagen Matrix Implant in Glaucoma Surgery.

Four patients with progressive glaucoma and inadequate intraocular pressure control despite maximal medical therapy underwent non-penetrating deep sclerectomy with a biodegradable collagen-glycosaminoglycan implant and…

Turk J OphthalmolOct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

The role of sexual mindfulness in enhancing sexual well-being among breast cancer survivors: A randomized clinical trial.

This randomized clinical trial assessed sexual mindfulness training for sexual well-being among women with breast cancer attending health service centers in Shahrekord, Iran.

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportUrology

Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.

A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.

Int Braz J UrolOct 23, 2026Read case
Clinical ResearchNeurologyOpen access

STN-SNr co-stimulation in Parkinson's disease: a systematic review and meta-analysis of motor and freezing-of-gait outcomes.

This systematic review and meta-analysis assessed whether adding substantia nigra pars reticulata stimulation to subthalamic nucleus deep brain stimulation improves motor function or freezing of gait in people with…

Neurol SciOct 23, 2026Read summary
Clinical ResearchGastroenterology

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.

This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.

Liver IntOct 23, 2026Read summary
Case ReportNeurologyOpen access

Spontaneous regression of post-traumatic syringomyelia: longitudinal mr imaging demonstrating a dynamic disease course.

A 69-year-old patient with post-traumatic cervicothoracic syringomyelia presented with occipital headaches, dizziness, and subjective upper-extremity weakness.

Spinal Cord Ser CasesOct 23, 2026Read case
Clinical ResearchObstetrics & Gynecology

Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.

PLoS OneOct 23, 2026Read summary
Clinical ResearchGeriatrics

A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.

This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.

J Vis ExpOct 23, 2026Read summary
Case ReportNeurology

Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.

A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.

J Peripher Nerv SystOct 23, 2026Read case

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