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2000 articles

October 202624

Clinical ResearchHematology

Tagraxofusp, azacitidine, and venetoclax for blastic plasmacytoid dendritic cell neoplasm.

This phase 2 clinical trial evaluated tagraxofusp, azacitidine, and venetoclax in 27 patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN): 16 previously untreated and 11 with relapsed or refractory…

BloodOct 29, 2026Read summary
Clinical ResearchNeurology

Levodopa or dopamine agonists for enhancing motor function after stroke.

This Cochrane systematic review and meta-analysis assessed whether levodopa or dopamine agonists improve motor function after stroke.

Cochrane Database Syst RevOct 29, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Primary care cardiovascular risk reduction after pregnancy complications: a qualitative systematic review.

This qualitative systematic review examined women’s experiences of behavioural change to reduce cardiovascular risk after adverse pregnancy outcomes (APOs), drawing on studies from high-income countries with universal…

Br J Gen PractOct 29, 2026Read summary
Clinical ResearchOncology (Medical)Open access

What are the palliative and end-of-life care needs and preferences of people with cancer from culturally and linguistically diverse (CALD) backgrounds?: A systematic review.

This systematic review synthesised evidence on palliative and end-of-life care needs and preferences among people with cancer from culturally and linguistically diverse (CALD) backgrounds, and on factors affecting…

Support Care CancerOct 29, 2026Read summary
Clinical ResearchInfectious Diseases

Schistosoma-Salmonella co-infection in Africa: Epidemiology, biological mechanisms, and antimicrobial resistance: A systematic review and meta analysis.

This systematic review and meta-analysis synthesized evidence on the epidemiology, proposed biological mechanisms, and antimicrobial resistance associated with Schistosoma–Salmonella co-infection in Africa.

PLoS OneOct 29, 2026Read summary
Clinical ResearchPsychiatry

From Daily Attitudes to Alcohol-Related Harm: A Within-Person Serial Mediation Test Informed by the Theory of Planned Behavior.

This multilevel daily-diary study examined whether day-to-day changes in attitudes toward heavy drinking were linked to alcohol-related harm through intentions and consumption.

Alcohol Clin Exp Res (Hoboken)Oct 29, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Infantile posterior fossa atypical teratoid/rhabdoid tumor: navigating diagnostic complexity and molecular paradigms.

A female infant younger than 1 year presented with a massive cystic-solid posterior fossa tumor and rapidly developing obstructive hydrocephalus.

Childs Nerv SystOct 29, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

Community-based nutrition interventions across the continuum of care in humanitarian settings: a systematic review and evidence map.

This systematic review and evidence map examined community-based nutrition interventions in humanitarian and emergency settings in low- and middle-income countries.

Public Health NutrOct 29, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effect of fasting and postprandial states on thyroid function test parameters and diagnostic interpretation: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether fasting versus postprandial sampling affects thyroid function tests and diagnostic classification.

EndocrineOct 29, 2026Read summary
Clinical ResearchPediatrics

Human milk oligosaccharide (2'-FL) modifies the gut microbiome in children after bone marrow transplant.

This prospective phase 1/2 clinical trial evaluated daily oral 2′-fucosyllactose (2′-FL), a human milk oligosaccharide, from conditioning through day +30 in children undergoing allogeneic hematopoietic stem cell…

BloodOct 29, 2026Read summary
Case ReportMedical Genetics

PIH1D2 Loss-of-Function Directs Ciliary and Cell Cycle Defects Resulting in Left Isomerism With or Without Biliary Atresia.

Two unrelated patients with left isomerism heterotaxy were found by genome sequencing to have biallelic loss-of-function variants in PIH1D2.

Liver IntOct 29, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Robot-assisted minimally invasive versus conventional open transforaminal lumbar interbody fusion for lumbar degenerative disease: a prospective randomized controlled trial.

This prospective, single-centre, assessor-blinded randomized trial compared robot-assisted minimally invasive TLIF with conventional fluoroscopy-guided open TLIF in 128 patients with lumbar degenerative disease.

J Robot SurgOct 29, 2026Read summary
Clinical ResearchEmergency Medicine

Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.

This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.

Emerg Med AustralasOct 29, 2026Read summary
Case ReportOtolaryngology (ENT)

Tracheoscopic Management of Postoperative High Tracheoesophageal Fistula Using Covered Self-Expanding Metallic Stents: A Comparative Report of 2 Cases With Divergent Outcomes.

Two men developed high tracheoesophageal fistulas after esophageal cancer surgery. In the 67-year-old, a 0.6 cm fistula 4 cm below the vocal folds was treated with a straight covered self-expanding metallic stent; after…

Am J Case RepOct 29, 2026Read case
Case ReportInfectious Diseases

Establishing Potosi Virus as a Human Pathogen: Fatal Neuroinvasive Disease in a B-Cell-Depleted Patient.

A 37-year-old woman with multiple sclerosis receiving long-term rituximab developed rapidly progressive dementia. MRI showed progressive generalized atrophy, while cerebrospinal fluid had only transient, minimal…

NeurologyOct 29, 2026Read case
Clinical ResearchPediatricsOpen access

Timing of intratracheal administration of budesonide mixed with surfactant to prevent bronchopulmonary dysplasia: a systematic review and meta-analysis.

This systematic review and meta-analysis examined randomised trials comparing intratracheal budesonide mixed with surfactant against surfactant alone in infants, assessing bronchopulmonary dysplasia (BPD) and whether…

Eur J PediatrOct 29, 2026Read summary
Clinical ResearchPediatrics

Effect of nutrition counseling on complementary feeding practices among mothers with children aged 6-23 months in West Gojjam Zone, Northwest Ethiopia: A cluster-randomized controlled trial.

This two-arm, parallel cluster-randomized controlled trial assessed Health Belief Model-based nutrition counseling for mothers of children aged 6–23 months in rural West Gojjam Zone, Northwest Ethiopia.

PLoS OneOct 29, 2026Read summary
Clinical ResearchDermatology

Effectiveness of a Ceramide-Based Lamellar Emulsion on Skin Barrier Function in Surgical Nurses: A Randomized Controlled Trial.

This single-center randomized controlled trial assessed whether a ceramide-based lamellar emulsion improved hand skin barrier function in surgical nurses exposed to frequent perioperative hand hygiene.

AORN JOct 29, 2026Read summary
Case ReportGastroenterology

Magnesium oxide tablets form rigid masses in xanthan gum-based thickeners: A physicochemical hazard revealed by a clinical case.

An older adult with a malignant esophageal stricture developed acute esophageal obstruction from a foreign body identified as a swollen, non-disintegrated magnesium oxide (MgO) tablet.

PLoS OneOct 29, 2026Read case
Clinical ResearchGeriatrics

The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.

Geriatr Gerontol IntOct 29, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of High-Frequency Transcranial Magnetic Stimulation Therapy for Depression With Insomnia Symptoms: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials.

This systematic review and meta-analysis of randomized controlled trials assessed left dorsolateral prefrontal cortex-targeted high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for people with…

Brain BehavOct 29, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Ergonomic interventions for treating work-related complaints of the arm, neck or shoulder in adults.

This Cochrane systematic review and meta-analysis assessed ergonomic interventions for work-related arm, neck or shoulder complaints (CANS) in adults.

Cochrane Database Syst RevOct 28, 2026Read summary
Case ReportPediatrics

A Case of Delayed Detection of Vertical Transmission of HIV-1 Due to Maternal Therapy With Long-Acting Injectable Cabotegravir Plus Rilpivirine.

A 4-month-old infant was diagnosed with HIV-1 after in utero exposure to maternal antiretroviral therapy with long-acting injectable cabotegravir plus rilpivirine (LA-CAB/RPV) during the third trimester.

Clin Infect DisOct 28, 2026Read case
Clinical ResearchOrthopedic Surgery

Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.

This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.

Musculoskeletal CareOct 28, 2026Read summary

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