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1502 articles
October 202624
Image-guided moderately hypofractionated proton beam therapy for localized prostate cancer: 5-year outcomes of a phase II trial.
This phase II clinical trial evaluated image-guided, moderately hypofractionated proton beam therapy (63 Gy RBE in 21 fractions) in 125 men with histologically confirmed localized prostate cancer (cT1c-3aN0M0).
Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.
This assessor-blinded, multicentre randomised controlled trial evaluated 16 weeks of home-based, real-time remotely supervised high-intensity interval training (HIIT) in children and adolescents aged 6–20 years with…
Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial.
This pre-specified analysis of the multicentre, randomised DECISION trial examined blinded withdrawal of long-term low-dose digoxin or placebo in patients with heart failure and reduced or mildly reduced ejection…
Sex differences in pharmacological treatment of heart failure: a meta-analysis of randomized trials.
This systematic review and meta-analysis examined sex differences in pharmacological treatment effects across randomized heart failure trials and whether women’s representation influenced estimated efficacy.
Faith-based organisations in providing HIV services within low- and middle-income countries (LMICs): a systematic review.
This systematic review assessed empirical studies of faith-based organisations (FBOs) delivering HIV services in low- and middle-income countries.
Assessing sexual exposure to oxaliplatin in vaginal secretions during FOLFOX chemotherapy: a case report.
A 54-year-old woman with stage IIIA rectal cancer collected vaginal swabs and urine for five consecutive days during two FOLFOX chemotherapy cycles.
Over-dispersion in malaria-schistosoma co-infection: insights from a meta-analytical approach and systematic review.
This systematic review and meta-analysis assessed malaria–schistosomiasis co-infection patterns in endemic settings, primarily in sub-Saharan Africa, and tested whether co-infections exceeded levels expected if the…
Women's experiences of a medically supervised fasting intervention for infertility: a qualitative study.
Nested within a randomized controlled trial of medically supervised prolonged fluid-only fasting (< 500 kcal/day) for infertility, this qualitative study explored women’s experiences of the intervention.
The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial.
This first-in-human, phase I dose-escalation and expansion trial evaluated continuous daily roginolisib in patients with solid and haematologic malignancies.
A Step-by-Step Protocol for Manual Reduction and Splint Immobilization of Distal Radius Fractures.
A 53-year-old woman presented with a dorsally displaced fracture of the left distal radius. Before reduction, radiographs showed a volar tilt of approximately -15° and radial inclination of approximately 1.74°.
The Surgical Management of Prostate Cancer in Renal Transplant Recipients: The Minimally Invasive Approach.
A 66-year-old man with localized Gleason 3 + 4 = 7a prostate cancer and a functioning renal transplant in the right iliac fossa underwent nerve-sparing robot-assisted radical prostatectomy with bilateral pelvic…
Rhabdomyolysis Following Robot-Assisted Radical Prostatectomy.
A 66-year-old man with obesity, insulin-dependent diabetes, and multiple comorbidities underwent robot-assisted radical prostatectomy for cT3a cN1 prostate cancer, with approximately 4 hours of console time.
Efficacy and Safety of Saffron and Ashwagandha for Stress-Related Mental Health Outcomes: A Systematic Review of Randomized Controlled Trials.
This PRISMA-compliant systematic review synthesised randomised controlled trial evidence on saffron and ashwagandha for stress-related mental health outcomes. It included 31 RCTs among 34 eligible studies.
Low-Frequency Repetitive Transcranial Magnetic Stimulation with Sensory Arousal Nursing for Post-Stroke Dysphagia.
This single-center, randomized, assessor-blinded study evaluated low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with sensory arousal nursing versus routine nursing in 160 patients with acute…
Stakeholder Perspectives on Digital Health Technologies in Poststroke Self-Management and Rehabilitation: Systematic Review Based on the NASSS Framework.
This systematic review synthesized stakeholder perspectives on digital health technologies (DHTs) for poststroke self-management and rehabilitation, mapping findings to the NASSS framework.
Comparison of the Efficacy of Appiani and Zuma Maneuvers in Patients with Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo.
This prospective randomized comparative study evaluated the Appiani and Zuma repositioning maneuvers in patients with unilateral apogeotropic horizontal canal benign paroxysmal positional vertigo.
Etrasimod reduces circulating and mucosal inflammatory lymphocyte populations and alters innate immune and non-immune cell signatures in intestinal mucosa: ELEVATE UC phase 3 clinical data.
This analysis of the phase 3 ELEVATE UC randomised trials characterised blood and intestinal mucosal changes in patients with ulcerative colitis treated with etrasimod or placebo.
Effect of pre-visit computer-assisted history-taking with a structured copy-ready summary on documentation completeness in screening for inflammatory rheumatic diseases: a randomized pilot study.
This multicenter, parallel-group randomized pilot study assessed pre-visit computer-assisted history-taking (CAHT) with a structured, copy-ready summary in adults at increased risk of inflammatory rheumatic disease…
A pedicled buccal fat pad for paranasal volume augmentation in orthognathic surgery: a case report.
A patient with a round face and maxillary hypoplasia underwent orthognathic surgery, but the maxilla could not be advanced as far as desired for dental and aesthetic reasons.
Effects of Sodium Bicarbonate Ringer's Solution versus Lactate Ringer's Solution on Emergence Time in Patients Undergoing Supratentorial Tumor Resection: A Randomized Controlled Trial.
This randomized controlled trial compared intraoperative sodium bicarbonate Ringer’s solution (BRS) with lactated Ringer’s solution (LRS) in patients undergoing elective supratentorial tumor resection.
Extracorporeal Cardiopulmonary Resuscitation as a Bridge to Cardiac Transplantation in Refractory Cardiac Arrest Due to Fulminant Myocarditis: A Case Report.
A previously healthy 36-year-old woman presented with fulminant myocarditis and cardiogenic shock, then sustained an in-hospital cardiac arrest that did not respond to conventional CPR.
Tofacitinib 20 vs 30 mg in acute severe ulcerative colitis: a double-blind randomized controlled trial.
This double-blind, pilot randomized controlled trial compared tofacitinib 20 mg/day with 30 mg/day, each given alongside intravenous corticosteroids, in adults with acute severe ulcerative colitis.
Time-restricted feeding with resistance training is not superior to conventional feeding for body composition and muscle strength: a systematic review and meta-analysis.
This systematic review and meta-analysis examined time-restricted feeding (TRF) versus conventional diets in healthy adults aged 18 or older undertaking resistance training.
Effects of complementary therapies on physiological and psychological outcomes in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled 36 randomized controlled trials involving 3148 people with COPD to assess complementary therapies, including exercise-based and psychological approaches.
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