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1566 articles
October 202624
Refractory amiodarone-induced thyrotoxicosis causing malignant arrhythmias, treated with therapeutic plasma exchange-bridged thyroidectomy.
A man in his mid-60s with severe cardiomyopathy developed refractory amiodarone-induced thyrotoxicosis, leading to recurrent ventricular tachycardia.
Reduced venesection requirement as a clue to occult colorectal cancer in hereditary haemochromatosis.
A man in his late 70s with hereditary haemochromatosis experienced an unexpected cessation of his usual venesection for iron management, despite no gastrointestinal symptoms or anemia.
Cutaneous tumbu fly myiasis in a returning child traveller and a novel EMLA-assisted extraction technique in paediatric emergency care.
A toddler presented with cutaneous myiasis and cellulitis after traveling to Gambia, caused by Cordylobia anthropophaga. The case was managed using a novel non-operative technique involving eutectic mixture of local…
Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.
A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.
Comprehensive dental management of odontogenic infection and ankyloglossia under general anaesthesia in a medically complex child with intellectual disability.
A middle childhood child with moderate intellectual disability presented with pain and swelling in the right posterior mandibular area.
Peritoneal loose body: an incidental finding, a challenging diagnosis and multimodal assessment to avoid resections.
A man in his early 40s presented with urinary symptoms and was found to have a right ureteric calculus, hydronephrosis, and a urinary tract infection.
Myxoedema coma in a patient with alcohol dependence: a diagnostic pitfall.
A man in his sixties with known hypothyroidism and alcohol dependence presented with profound hypothermia, refractory hypoglycaemia, hypoxia, and reduced consciousness.
Uveitis despite adalimumab therapy in Blau syndrome.
A middle childhood boy initially diagnosed with oligoarticular juvenile idiopathic arthritis presented with persistent arthritis, recurrent fever, and skin lesions.
Unexpected parasternal musculature during skin-sparing mastectomy and microvascular breast reconstruction.
A woman in her late 40s underwent bilateral skin-sparing mastectomy and immediate autologous breast reconstruction. During the procedure, bilateral sternalis muscles were unexpectedly identified.
Fulminant multi-organ failure associated with cereulide-producing Bacillus cereus after consumption of improperly stored rice.
A previously healthy male in his 20s presented with generalized seizures and severe hypoglycemia after eating improperly stored reheated rice.
Fatal drug-induced liver injury in the setting of abemaciclib therapy for metastatic breast cancer.
A Hispanic woman in her mid-60s with metastatic ER+/HER2- breast cancer developed severe mixed hepatocellular-cholestatic injury one month after starting abemaciclib with letrozole.
Multisystem imaging findings as diagnostic red herrings in Wilson's disease.
A previously healthy man in his 20s presented with fever, cough, jaundice, and a right-sided pleural effusion. Initial tests revealed significant hepatic dysfunction, and imaging showed cirrhotic liver morphology…
Acute autoimmune hepatitis diagnosed concurrently with human immunodeficiency virus.
A woman in her 50s presented with jaundice and severe hepatocellular injury, later diagnosed with advanced HIV infection. Initial considerations included infectious hepatitis, but serology, imaging, and liver biopsy…
Coarctation of the aorta as the presenting cardiovascular manifestation of Williams syndrome in an infant.
A male infant presented for pre-operative evaluation of a left inguinal hernia, during which discrete juxtaductal coarctation of the aorta was incidentally found.
Iatrogenic Cushing's syndrome from an adulterated glucocorticoid-containing supplement.
A man in his 40s presented with rapid weight gain, fatigue, and signs of Cushing's syndrome, including abdominal striae and centripetal obesity.
Boomerang-shaped extended latissimus dorsi flap for combined breast reconstruction and body contouring following massive weight loss.
A patient with a history of massive weight loss sought correction for her left-sided implant-based breast reconstruction, which had resulted in poor cosmetic outcomes and persistent pain.
Incidental discovery of a massive primary retroperitoneal serous cystadenoma following trauma.
A woman in her 70s presented with severe abdominal pain after a fall. Imaging revealed a massive cystic lesion in the left retroperitoneum, which was confirmed to be a ruptured cyst.
Follow-up colonoscopy after abnormal stool-based colorectal cancer screening: a systematic review of completion, timeliness and implementation strategies.
This systematic review examined the completion rates and timeliness of diagnostic colonoscopy following abnormal stool-based colorectal cancer screenings in adults.
PHOENIX: a study protocol for a pilot randomised controlled trial of pre-emptive pharmacogenomic panel testing in acute care settings with health economic evaluations.
The PHOENIX trial is a pilot randomized controlled trial assessing the impact of pre-emptive pharmacogenomic panel testing on adverse drug reactions (ADRs) and treatment failures in acute care settings.
Efficacy and safety of erythrocytapheresis in chronic mountain sickness: a randomised controlled trial protocol (ESCAPE-CMS).
This randomized controlled trial protocol investigates the efficacy and safety of erythrocytapheresis in patients with chronic mountain sickness (CMS), a condition affecting over 4 million individuals at high altitudes.
Home-based neuro-cardiac rehabilitation in congenital heart disease: the QUALINEURO-REHAB trial study protocol.
The QUALINEURO-REHAB trial is a multicenter, two-arm randomized controlled trial assessing a home-based neuro-cardiac rehabilitation program in youth aged 8-25 with complex congenital heart disease (CHD).
Machine Learning and Deep Learning for the Diagnosis of Cervical Degenerative Diseases: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated traditional machine learning (TML) and deep learning (DL) approaches for diagnosing cervical degenerative diseases, analyzing data from 30 studies involving 25,301…
Efficacy of a Prescription-Based Mobile Digital Therapeutic as an Adjunct to Pharmacotherapy for the Acute Phase of Panic Disorder: Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial evaluated the efficacy of a prescription-based mobile digital therapeutic (DTx) as an adjunct to pharmacotherapy in 66 patients with acute-phase panic disorder.
Serum ferritin in children with Attention Deficit Hyperactivity Disorder (ADHD): A systematic review and meta-analysis.
This systematic review and meta-analysis examined serum ferritin levels in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to healthy controls.
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