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1566 articles

October 202624

Case ReportGastroenterology

A novel variant of pancreaticobiliary maljunction: Complete opening of the common bile duct into the duct of Santorini in a patient with pancreas divisum.

A 20-year-old woman with recurrent cholestasis and acute pancreatitis presented with fever, jaundice, and abdominal pain; laboratory findings supported cholangitis and pancreatitis.

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Case ReportHematology

Spontaneous splenic rupture in a patient with congenital factor XIII deficiency: A case report and literature review.

A 32-year-old man with congenital factor XIII deficiency presented with sudden abdominal pain and hypovolemic shock. Contrast-enhanced abdominal CT showed a large perisplenic hematoma, and surgery confirmed splenic…

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Case ReportOrthopedic Surgery

Trauma-related simultaneous asymmetric bilateral hip dislocation: A case report.

A 27-year-old man sustained simultaneous dislocations of both hips after high-energy trauma: the left hip was anteriorly dislocated and the right posteriorly.

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Clinical ResearchInfectious Diseases

Development of HOPES Intervention for a Randomized Controlled Trial to Reduce the Perceived Stigma Among Women Living With HIV/AIDS in China.

This study developed and pilot-tested HOPES, a culturally grounded WeChat program intended to reduce HIV-related stigma among Chinese women living with HIV/AIDS.

AIDS Educ PrevOct 1, 2026Read summary
Clinical ResearchCardiology

National and Subnational Trends in Ischemic Heart Disease Burden in Iran, 1990-2023: A Systematic Review.

This systematic review synthesized national and subnational evidence on ischemic heart disease (IHD) in Iran from 1990 to 2023, including model-based estimates and empirical studies.

Clin CardiolOct 1, 2026Read summary
Clinical ResearchGeneral Surgery

The Acceptability and Experiences of Participating in a Preoperative Intentional Weight-Loss Programme From Diagnosis to Surgery for Colorectal Cancer.

This qualitative study, embedded in the CARE randomised controlled trial, explored how patients with colorectal cancer experienced an intensive, dietitian-supported weight-loss programme between diagnosis and surgery.

Health ExpectOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE-AIM-based systematic review.

This PRISMA-guided systematic review assessed the internal and external validity of digital interventions for psychological and cognitive concerns among people with cancer, caregivers, and family members, using the…

Appl Psychol Health Well BeingOct 1, 2026Read summary
Case ReportHematology

Retrospective RNA Sequencing Reclassifies a Historical t(5;12) Eosinophilic Neoplasm From Presumed PDGFRB Rearrangement to ETV6::ACSL6.

A woman with a chronic eosinophilic myeloid neoplasm had a t(5;12) that raised suspicion of PDGFRB involvement, but contemporary testing did not identify a rearrangement and empiric imatinib produced no meaningful…

Genes Chromosomes CancerOct 1, 2026Read case
Clinical ResearchNeurology

Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.

This exploratory analysis pooled participants from the randomized phase 3 ENGAGE and EMERGE aducanumab trials who entered a long-term extension or later redosing study.

Alzheimers DementOct 1, 2026Read summary
Clinical ResearchGastroenterology

Effect of a Computer-Aided Device on Endoscopists' Biopsy Practice for Gastric Neoplasms: A Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial compared AI-assisted with standard gastric screening, examining biopsy practice for documented lesions.

Dig EndoscOct 1, 2026Read summary
Clinical ResearchGeriatrics

Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review.

This systematic review examined longitudinal patterns of depressive symptoms and their predictors among adults aged 60 years or older.

Brain BehavOct 1, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.

A bilateral transtibial amputee had a modified tibiofibular synostosis (TFS) stump on the right and a conventional Burgess-type stump (BTS) on the left.

BMC Musculoskelet DisordOct 1, 2026Read case
Clinical ResearchRheumatology

First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.

This systematic review and meta-analysis of randomized trials compared initial biologic and targeted synthetic DMARDs (b/tsDMARDs), alone or with methotrexate, against methotrexate in methotrexate-naïve adults with…

Rheumatology (Oxford)Oct 1, 2026Read summary
Clinical ResearchGeneral Surgery

Cross-Linked Chondroitin Sulfate Adhesion Barrier System in Open Rectal Resection: A Randomized Clinical Trial.

This multicenter, prospective, randomized, open-label trial with blinded endpoint assessment evaluated powdered cross-linked chondroitin sulfate (SI-449) in adults undergoing open rectal resection for rectal cancer.

JAMA SurgOct 1, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Incisional Negative Pressure Wound Therapy for Prevention of Surgical Site Infection: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled 85 randomised clinical trials involving 16,980 adults with primarily closed surgical incisions to compare incisional negative pressure wound therapy (iNPWT) with standard…

JAMA SurgOct 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Preoperative High-Dose Corticosteroids in Digestive Cancer Surgery: A Randomized Clinical Trial.

This multicenter, double-blind, placebo-controlled superiority randomized trial assessed whether preoperative high-dose corticosteroids improve outcomes after elective, curative-intent surgery for digestive cancer.

JAMA SurgOct 1, 2026Read summary
Clinical ResearchRheumatology

Bimekizumab efficacy in male and female patients with axial spondyloarthritis: 52-week results from the phase 3 BE MOBILE trials.

This post hoc analysis of two phase 3 randomised trials assessed sex-based differences in bimekizumab response among patients with radiographic or non-radiographic axial spondyloarthritis.

Rheumatology (Oxford)Oct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed randomised trials of psychological and psychosocial interventions targeting auditory hallucinations in adults with schizophrenia spectrum disorders.

JAMA PsychiatryOct 1, 2026Read summary
Clinical ResearchPsychiatry

Social Determinants of Health and Neurobiology Across the Schizophrenia Course: A Systematic Review.

This systematic review examined associations between adverse social determinants of health and brain measures in people across the schizophrenia spectrum, including those at elevated risk.

JAMA PsychiatryOct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Dose Considerations and Generalization Following Script Training for Poststroke Aphasia: A Randomized Factorial Clinical Trial.

This single-site, single-blind, 2 × 2 factorial randomized controlled trial examined how script length and session frequency affect treatment outcomes in 85 people with chronic poststroke aphasia.

J Speech Lang Hear ResOct 1, 2026Read summary
Clinical ResearchPsychiatry

Online stepped care for the treatment of posttraumatic stress disorder: A randomized controlled noninferiority trial.

This randomized controlled non-inferiority trial compared online stepped care with telehealth cognitive processing therapy (CPT) in 84 adults with PTSD or subthreshold PTSD.

Behav Res TherOct 1, 2026Read summary
Clinical ResearchPsychiatry

Who is getting better in treatment? Dynamics in risk processes as a signature of short-term suicide treatment response.

This analysis of adults receiving up to 12 sessions of suicide-focused therapy within a randomized clinical trial examined whether weekly patterns in suicide risk and resilience differed according to suicide attempts…

J Affect DisordOct 1, 2026Read summary
Clinical ResearchPediatrics

Sensory processing and executive functioning interaction in neurodevelopmental disorders and at-risk conditions: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between sensory processing (SP) and executive functioning (EF) in children and adolescents aged 0–18 with neurodevelopmental disorders or at-risk…

Neurosci Biobehav RevOct 1, 2026Read summary
Case ReportPediatrics

Persistent influenza A RNA detection in a fatal pediatric case of influenza-associated encephalopathy.

A 9-year-old boy developed fulminant influenza-associated encephalopathy, a life-threatening complication of influenza. Despite life-sustaining support, intensive immunomodulatory treatment, and antiviral therapy…

J Infect Public HealthOct 1, 2026Read case

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