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1616 articles
October 202624
A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.
An Iranian girl presented with developmental delay, hypotonia, and refractory seizures. Whole-exome sequencing identified a de novo CDKL5 frameshift variant, c.1037_1038delTCinsCAGATCTAA (p.Ile346Thrfs*14), which Sanger…
Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.
This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.
Multiple Recurarization Episodes After Sugammadex Reversal in Hyperthermic Intraperitoneal Chemotherapy: A Case Report.
A 53-year-old woman undergoing hyperthermic intraperitoneal chemotherapy (HIPEC) experienced three sequential episodes of recurarization after reversal of rocuronium-induced neuromuscular blockade with sugammadex 5.4…
Kinematic adaptations of the uppercut punch following an eight-week biomechanics-based training intervention in amateur boxers.
This randomized controlled trial examined whether an eight-week biomechanics-based program changed right-hand uppercut mechanics in 24 male amateur boxers with 3–4 years of training experience.
Case Report WIN-MTB-2024001 - WIN International Molecular Tumor Board: A 55-year-old male with glioblastoma exhibiting amplifications in MDM2 and EGFR.
A 55-year-old man with high-grade glioblastoma had next-generation sequencing findings that included MDM2 and EGFR amplifications and a CDKN2A frameshift mutation.
WIN-MTB-2024002 - WIN International Molecular Tumor Board: A 52-year-old female with unmeasurable Stage IIIc colon cancer.
A 52-year-old woman with stage IIIc colon cancer had KRAS, TP53, IDH1, and APC mutations, high tumor PD-L1 expression, and elevated VEGFR1 and VEGFR3.
En bloc excision of a large hydatid cyst originating from the posterior wall of the left ventricle.
A male patient was found incidentally to have a hydatid cyst arising from the posterior wall of the left ventricle. The cyst was completely removed en bloc through a left ventriculotomy.
Nociception Level-Guided Multimodal Analgesia with External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy.
This double-blind randomized controlled trial compared nociception level (NOL)-guided multimodal analgesia (MMA) incorporating an external oblique intercostal plane (EOIP) block with intravenous dexketoprofen alone in…
Arthroscopic Matrix Augmentation of Partial-Thickness Rotator Cuff Tear Repairs Using a Full-Thickness Human Perinatal Tissue Allograft.
Two patients with persistently symptomatic partial-thickness rotator cuff tears underwent arthroscopic perinatal tissue membrane allograft matrix augmentation using an onlay technique after conservative care failed.
Clinical Improvement Following Multimodal Treatment in Depersonalization-Derealization Disorder: A Case Report.
A patient with depersonalization-derealization disorder presented with derealization, emotional blunting, poor memory, slowed reactions, and impaired attention.
Vacuum-Assisted Breast Biopsy and Excision for Breast Lesions: A Systematic Review and Meta-analysis of Malignant Upgrade in B3 Lesions.
This systematic review and meta-analysis examined malignant upgrade in B3 breast lesions assessed through diagnostic vacuum-assisted biopsy (VAB/VABB) or second-line vacuum-assisted excision (VAE).
Impact of Phosphatidylinositol 3-Kinase and B-Raf Mutations in Rat Sarcoma Wild-Type Metastatic Colorectal Cancer.
This systematic review and meta-analysis assessed whether PIK3CA and BRAF mutations were associated with outcomes among patients with RAS wild-type metastatic colorectal cancer receiving first-line EGFR inhibitor…
Mixed Pneumonia with Pulmonary Embolism and Multiple Pathogens Detected in Bronchoalveolar Lavage Fluid: A Case Report.
A 72-year-old man presented with fever, nonproductive cough, vomiting, hypoxemia, elevated inflammatory markers, and an elevated D-dimer.
Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.
Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.
Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.
This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.
Effects of blood flow restriction training in adult upper-limb musculoskeletal rehabilitation: A systematic review.
This systematic review assessed the clinical effects, tolerability, and prescription of blood flow restriction training (BFRT) in adults undergoing rehabilitation for upper-limb musculoskeletal conditions.
Ectopic thyroid tissue accompanied by distinct blood supply and lymphoid tissue within the carotid sheath - a case report.
A 42-year-old man had an asymptomatic right-sided neck mass detected during a routine examination. Ultrasound showed a normally located thyroid and a well-defined 1.3 cm × 0.9 cm × 0.5 cm mass with echotexture similar…
A case of neonatal gastric perforation misdiagnosed as neonatal necrotizing enterocolitis: A literature review.
A male infant born at 33 weeks and 5 days presented on day four of life with abdominal distension, feeding refusal, and no passage of flatus or stool.
Effectiveness of kinesio tape in the treatment of patients with plantar fasciitis: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed kinesio tape (KT) for plantar fasciitis, including 16 randomized controlled trials.
Repetitive transcranial magnetic stimulation for the treatment of restless legs syndrome: A meta-analysis.
This meta-analysis examined repetitive transcranial magnetic stimulation (rTMS) versus sham stimulation for restless legs syndrome (RLS), pooling four eligible studies.
Additive effects of active vitamin D3 or vitamin E administration on therapeutic lower-limb home exercise for knee osteoarthritis: A pilot prospective randomized controlled trial.
This pilot prospective randomized controlled trial assessed whether active vitamin D3 or vitamin E added benefit to home exercise in postmenopausal women with symptomatic knee osteoarthritis.
The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.
This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.
Presumed oxaliplatin-related Guillain-Barré syndrome: A case report and review of chemotherapy-related Guillain-Barré syndrome.
A 77-year-old woman with metastatic cholangiocarcinoma and colorectal carcinoma developed rapidly progressive, symmetric ascending motor weakness about 2 weeks after her last cycle of gemcitabine, oxaliplatin…
Effectiveness of traditional mind-body exercises on fall risk test scores and balance in older adults: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled 31 randomized controlled trials involving 3,622 older adults to assess traditional mind-body exercises and fall-risk test scores and balance.
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