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1616 articles

October 202624

Clinical ResearchOrthopedic Surgery

Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .

This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.

This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchNeurology

From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.

This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchPulmonology

Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.

This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.

Rev Med VirolOct 26, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.

This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.

J Manag Care Spec PharmOct 26, 2026Read summary
Clinical ResearchPediatrics

Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.

This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.

Scand J Med Sci SportsOct 26, 2026Read summary
Clinical ResearchDermatology

Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.

This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.

Eur J Clin InvestOct 26, 2026Read summary
Clinical ResearchPulmonologyOpen access

Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.

This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.

Eur J Sport SciOct 26, 2026Read summary
Clinical ResearchPsychiatryOpen access

An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.

This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…

Personal Ment HealthOct 26, 2026Read summary
Clinical ResearchCardiology

Safety of low lipoprotein(a) levels: the FOURIER trial.

This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…

Eur Heart JOct 26, 2026Read summary
Clinical ResearchCardiology

Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.

This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.

Eur Heart JOct 26, 2026Read summary
Clinical ResearchCardiology

Safety and Effectiveness of a Novel Laser-Based Intravascular Lithotripsy System for Coronary Calcium: FRACTURE Study.

FRACTURE was a prospective, multicenter, single-arm clinical trial evaluating a laser- and optic-based quad-emitter intravascular lithotripsy system in patients with severely calcified de novo coronary lesions.

JACC Cardiovasc IntervOct 26, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Association of Screen Time With Physical and Mental Health in University Students: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined screen-time duration and physical and mental health outcomes in university students aged 17 years or older.

J Med Internet ResOct 26, 2026Read summary
Clinical ResearchPediatrics

Outdoor risky play and health-related outcomes in children aged 3-12 years: A mixed-methods systematic review.

This mixed-methods systematic review synthesised evidence on outdoor risky play and health outcomes in children aged 3–12 years. It included 74 studies: 48 quantitative, 19 qualitative and 7 mixed-methods.

PLoS OneOct 26, 2026Read summary
Clinical ResearchGastroenterology

The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial.

This single-centre, prospective, double-blind randomised controlled trial compared a lidocaine ice popsicle containing simethicone and N-acetylcysteine (NAC) with a conventional lidocaine popsicle in 374 adults…

PLoS OneOct 26, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Evaluating gain and loss-framed mobile messaging to improve maternal health service uptake: A cluster randomized controlled trial in Jimma, Ethiopia.

This three-arm cluster-randomized controlled trial assessed whether gain- or loss-framed SMS messaging improved maternal health service use among 588 pregnant women in Jimma Zone, Ethiopia.

PLoS OneOct 26, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

The association between e-cigarette use and dyslipidemia: A systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis examined observational evidence on exclusive e-cigarette use and blood lipids in adults. Seven studies from four countries included 25,690 participants.

PLoS OneOct 26, 2026Read summary
Case ReportUrology

Testis-Sparing Surgery for Multiple Fibrous Pseudotumors of the Epididymis: A Case Report.

A 44-year-old man had multiple firm, nontender left epididymal nodules. Ultrasound showed hypoechoic lesions without testicular invasion, and tumor markers were negative.

Am J Case RepOct 26, 2026Read case
Case ReportUrologyOpen access

A rare twist after Ex-vivo RIRS: graft parenchymal urine leak in a living donor kidney.

A 29-year-old man received a living-donor kidney after ex-vivo retrograde intrarenal surgery (RIRS) to remove a 5 mm upper-pole calculus.

CEN Case RepOct 26, 2026Read case
Case ReportPediatricsOpen access

Long-term consequences in RAS blocker-induced fetopathy with multiorgan impairments.

A girl with fetopathy after maternal exposure to a renin–angiotensin system blocker was followed for 10 years. She had severe short stature and persistent mild developmental delay; cranioplasty at 1 year revealed right…

CEN Case RepOct 26, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Sialadenopapillary Ductal Tumor: Case Series and Review of the Literature.

The authors describe three patients with sialadenopapillary ductal tumors, a rare neoplasm of likely minor salivary gland origin characterized by prominent submucosal ductal proliferation and multilayered cystic…

Head Neck PatholOct 26, 2026Read case
Clinical ResearchNeurologyOpen access

Imaging Features and Prognosis of Anti‑Sez6l2 Encephalitis: A Longitudinal Cohort Study and Literature Review.

This longitudinal cohort study and systematic review examined clinical features, multimodal imaging, and treatment response in anti-Sez6l2 encephalitis.

CerebellumOct 26, 2026Read summary
Case ReportNeurologyOpen access

A closer look at LATE: a Case Report on a subtly evolving neurodegenerative disorder.

A 71-year-old presented with isolated episodic memory impairment, preserved global cognition, and intact daily function. Initial cerebrospinal fluid (CSF) Alzheimer’s disease (AD) biomarkers were negative, and 18F-FDG…

Neurol SciOct 26, 2026Read case
Clinical ResearchPsychiatryOpen access

Crisis Interventions for Children and Adolescents with Depression and Suicidality: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined crisis services for children and adolescents experiencing acute mental health crises, including severe depression, suicidal ideation, self-harm, and suicidal behaviour.

Curr Psychiatry RepOct 26, 2026Read summary

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