Trending archive
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1386 articles
October 202624
A Case of Delayed Detection of Vertical Transmission of HIV-1 Due to Maternal Therapy With Long-Acting Injectable Cabotegravir Plus Rilpivirine.
A 4-month-old infant was diagnosed with HIV-1 after in utero exposure to maternal antiretroviral therapy with long-acting injectable cabotegravir plus rilpivirine (LA-CAB/RPV) during the third trimester.
Impact of Intermittent Preventive Treatment for Malaria in Pregnancy With Sulfadoxine-Pyrimethamine, Dihydroartemisinin-Piperaquine, and Their Combination on Infant Outcomes: A Randomized Controlled Trial.
This double-blind randomized controlled trial compared infant malaria and growth outcomes after maternal intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine…
Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study.
This analysis of HELIOS-B, a double-blind, randomized, placebo-controlled trial, examined individual health-status components in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).
Impact of acoramidis on clinical stability in transthyretin amyloid cardiomyopathy: observations from ATTRibute-CM.
This post-hoc analysis of the phase 3, multicentre, randomised ATTRibute-CM trial assessed clinically meaningful changes in NT-proBNP or 6-minute walk distance among participants with transthyretin amyloid…
Mitral regurgitation in patients with heart failure and reduced ejection fraction: insights from GALACTIC-HF.
This analysis of the randomized, multicentre GALACTIC-HF trial examined mitral regurgitation (MR) and outcomes in patients with heart failure and reduced ejection fraction.
Targeted BRAF /MEK inhibition as a salvage therapy for patients with metastatic melanoma harboring a BRAF L597R mutation: two case reports and review of the literature.
Two patients with metastatic melanoma harboring the BRAF L597R mutation had rapid clinical deterioration and disease progression after dual immune checkpoint inhibition.
Acute pericarditis caused by Kocuria kristinae with successful withdrawal from hemodialysis: a case report.
A 47-year-old man developed dialysis-dependent acute kidney injury after severe heatstroke. About a month later, imaging showed a marked increase in cardiothoracic ratio, and echocardiography demonstrated a substantial…
A randomised controlled crossover trial comparing two mandibular repositioning appliances for treatment of moderate obstructive sleep apnoea.
This single-centre, randomised two-period crossover trial compared two custom-made mandibular repositioning appliances in 16 adults with moderate obstructive sleep apnoea.
Breastfeeding and maternal bone health 10 years postpartum: findings from the ROLO longitudinal cohort study.
This longitudinal cohort analysis examined whether breastfeeding behaviours were associated with maternal bone health 10 years after pregnancy.
Renal vein thrombosis with inferior vena cava extension and pulmonary embolism in a patient with acute pyelonephritis: a case report and updated literature review.
A previously healthy 29-year-old man presented with two weeks of left flank pain and fever. Contrast-enhanced CT showed acute left pyelonephritis and extensive renal vein thrombosis extending into the suprarenal…
Effect of intraoral glossopharyngeal nerve block on hemodynamic response to mouth retractor placement in transoral robotic surgery: a randomized clinical trial.
This prospective, single-centre randomized clinical trial assessed whether bilateral intraoral glossopharyngeal nerve block attenuates the blood-pressure response to mouth retractor placement during transoral robotic…
Germline BRCA-Lynch syndrome MINAS: report of six Argentinian families and a systematic review of the literature.
This report combined six Argentinian families with a systematic review of 40 publications to describe the phenotype of BRCA-Lynch syndrome (BRCA-LS) MINAS. The analysis included 92 patients from 69 families.
Comparison of sterile silicone studs and scalp infiltration with lignocaine for the attenuation of the hemodynamic and stress response to skull pin insertion during craniotomy in pediatric neurosurgical patients: a randomized controlled trial : Sterile silicone studs versus lignocaine infiltration for skull pin insertion.
This randomized controlled trial compared sterile silicone studs (SSS) with lignocaine infiltration for skull pin insertion in 64 children aged 12 years or younger undergoing neurosurgery.
Changes in gait function associated with cerebral small vessel disease-related cognitive impairment during dual-task walking: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dual-task (DT) gait measures distinguish people with cerebral small vessel disease-related cognitive impairment (CSVD-CI) from cognitively unimpaired controls…
Controlled postoperative red wine intake versus abstinence in habitual wine drinkers undergoing elective urological surgery (WISE): a translational randomized controlled trial assessing quality of life, surgical outcomes and complications.
This single-center randomized controlled trial compared postoperative abstinence with standardized red wine intake in habitual wine drinkers undergoing elective urological surgery.
Short-term effects of myofascial release with therapist-mediated transcutaneous electrical nerve stimulation in adolescent idiopathic scoliosis: an exploratory randomized controlled trial .
This assessor-blinded, exploratory randomized controlled trial evaluated short-term myofascial release with therapist-mediated transcutaneous electrical nerve stimulation (MFR-TENS) in 27 adolescents with idiopathic…
Efficacy and Safety of Short-Course Radiotherapy Alone or Combined With Consolidation Chemotherapy Versus Conventional Long-Course Chemoradiotherapy for Locally Advanced Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials.
This meta-analysis of randomized controlled trials compared short-course radiotherapy (SCRT), with or without consolidation chemotherapy, against long-course chemoradiotherapy (LCCRT) for locally advanced rectal cancer.
Obesity and perioperative outcomes of robotic-assisted surgery for endometrial cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative outcomes after robotic-assisted surgery for endometrial cancer in patients classified as obese or non-obese by the original studies.
Complex cervical venous drainage with a common facial-paralaryngeal anastomosis receiving the superior thyroid vein.
A 68-year-old woman’s archived CT angiogram showed a complex right cervical venous arrangement. The common facial vein and a separate lingual–parapharyngeal–paralaryngeal channel each drained into the right internal…
Pseudodominant inheritance in paraplegin (SPG7)-associated CPEO-ataxia syndrome.
A 47-year-old man presented with progressive external ophthalmoplegia, ptosis, gait disturbance and spasticity. Over ten years, he developed slowly progressive spastic ataxia with ocular motor involvement and neurogenic…
Left anterior laryngeal loop of the common carotid artery in a cluster of bilateral cervicothoracic vascular variants: a case report.
CTA demonstrated a common-origin left common carotid artery (CCA)–brachiocephalic trunk, a high-riding brachiocephalic trunk, and bilateral carotid and external carotid artery variants.
Comparative Effectiveness of Digital Exercise-Based Interventions for Improving Balance in Older Adults: Systematic Review and Network Meta-Analysis With GRADE Certainty of Evidence.
This systematic review and network meta-analysis compared five digital exercise-based approaches with conventional exercise (CE) and no treatment (NT) for balance in older adults.
Real-Time Electronic Patient-Reported Outcome Monitoring With Digital Triage and Care-Team Integration in Early Breast Cancer: ENABLE Randomized Controlled Trial.
The multicenter, open-label ENABLE randomized controlled trial compared weekly electronic patient-reported outcome (ePRO) screening with rule-based triage and care-team alerts against an active app-based support…
Post-transplant BRAF/MEK inhibitor maintenance sustains complete remission in BRAF V600E-mutant histiocytic sarcoma.
A patient with refractory BRAF V600E-mutant histiocytic sarcoma achieved complete remission with BRAF/MEK inhibition and then underwent allogeneic stem cell transplantation.
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