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782 articles
September 202624
List randomization for prevalence estimation of sensitive behavioral data among women with HIV of reproductive age in Lilongwe, Malawi.
This randomized controlled trial evaluated the effectiveness of list randomization in estimating the prevalence of sensitive behaviors among women of reproductive age living with HIV in Lilongwe, Malawi.
The clinical benefit of prostacyclin treatment in mechanically ventilated patients with SARS-CoV-2 infection is not attributed to anti-inflammatory effects.
This randomized controlled trial investigated the effects of iloprost on inflammatory and cytokine responses in 80 mechanically ventilated patients with SARS-CoV-2 infection and endotheliopathy.
The role of viral infections and other microbial factors in the pathogenesis of multiple sclerosis: a systematic review.
This systematic review assessed studies published from 2020 to 2025 on microbial factors and multiple sclerosis (MS) risk, activity, or progression.
Immunogenicity and safety of prophylactic HPV vaccines in people living with HIV: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the immunogenicity and safety of prophylactic HPV vaccines in people living with HIV (PLWH). The analysis included 12 studies with 1,493 participants for HPV16.
Rapid progression of a small penetrating aortic ulcer to rupture in the setting of Staphylococcus aureus bacteraemia.
An octogenarian woman with a history of heart failure and atrial fibrillation presented with cervical phlegmon and Staphylococcus aureus bacteraemia.
Efficacy of Empirical Antibiotics in Community-Based Management of Uncomplicated Severe Acute Malnutrition in Children: Protocol of a Randomized Controlled Trial.
This randomized controlled trial aims to evaluate the efficacy of 7-day amoxicillin versus single-dose azithromycin versus no antibiotics in promoting weight gain and nutritional recovery in children aged 6-59 months…
Neutralising antibodies and protection from progression to severe COVID-19: A meta-analysis.
This meta-analysis examined the relationship between vaccine-induced neutralising antibodies and protection from severe COVID-19 in individuals with SARS-CoV-2 infection.
The changing spectrum of cutaneous leishmaniasis and HIV coinfection in Bolivian Amazonia: a case report.
A 34-year-old man with advanced HIV infection presented with localized cutaneous leishmaniasis that progressed despite treatment with pentavalent antimonials.
Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of MRSA PCR nasal swab testing on vancomycin use in 277 adult ICU patients with suspected community-acquired pneumonia.
Impact of Wolbachia-infected Aedes aegypti on dengue incidence in endemic regions: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of Wolbachia-infected Aedes aegypti on dengue incidence in endemic regions.
A Randomized Clinical Trial to Compare Moxifloxacin Versus Azithromycin for the Treatment of Mycoplasma genitalium: The FARTHEST Study.
This randomized controlled trial evaluated the efficacy of moxifloxacin versus azithromycin for treating Mycoplasma genitalium in adults.
Fatal Transfusion-transmitted Severe Dengue in an Immunocompromised Host: Case Report and Systematic Literature Review.
A stem cell transplant recipient developed severe dengue following a blood transfusion during the 2024 dengue epidemic in Brazil.
Hypertension in a Randomized Trial of Dolutegravir- Versus Efavirenz-Based Antiretroviral Therapy in Pregnant and Postpartum Women with HIV.
This randomized controlled trial evaluated incident hypertension in 626 pregnant and postpartum women with HIV receiving different antiretroviral therapies: dolutegravir (DTG) + emtricitabine/tenofovir alafenamide…
Predictors of Treatment Failure in Children With HIV Starting First-line Antiretroviral Therapy in the ODYSSEY Trial.
The ODYSSEY trial investigated predictors of treatment failure in 381 children starting first-line antiretroviral therapy (ART), primarily in Africa.
Safety, Pharmacokinetics, and Pharmacodynamics of Single-Dose Programmed Cell Death Protein 1 Inhibitor, Budigalimab, in People With HIV-1 With Antiretroviral Therapy-Suppressed Viral Load.
This Phase 1b randomized controlled trial evaluated the safety, pharmacokinetics, and pharmacodynamics of single-dose budigalimab, a PD-1 inhibitor, in 32 people with HIV-1 on antiretroviral therapy.
Recombinant vs Standard Influenza Vaccine in Adults With Severe Obesity: A Randomized Clinical Trial.
This randomized clinical trial evaluated the immune response to recombinant influenza vaccine (RIV) versus standard-dose vaccine (SD) in adults with severe obesity (BMI ≥35 kg/m²).
Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared the efficacy of ceftolozane-tazobactam and ceftazidime-avibactam in treating multidrug-resistant Pseudomonas aeruginosa infections.
Safety and Tolerability of Oral Islatravir Once Monthly as Pre-exposure Prophylaxis in Cisgender Men and Transgender Women Who Have an Elevated Likelihood of HIV-1 Exposure: Results From the IMPOWER-24 Randomized Phase 3 Study.
The IMPOWER-24 randomized Phase 3 trial evaluated the safety and tolerability of monthly oral islatravir in cisgender men and transgender women at high risk for HIV-1 exposure.
Safety, Immunovirologic, and Central Nervous System Effects of PD-1 Inhibition in People With HIV Without Malignancy.
This phase 1 nonrandomized clinical trial evaluated the safety and effects of a single dose of pembrolizumab in 6 individuals with virally suppressed HIV.
Indirect Influenza Vaccine Effectiveness Under Randomized Conditions: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the indirect vaccine effectiveness (IVE) of influenza vaccines in non-institutional settings, analyzing data from 12 randomized controlled trials.
Recurrent severe cutaneous reaction to fluoroquinolones and rifampicin in a human immunodeficiency virus-positive patient with disseminated tuberculosis: A rare case report.
A 47-year-old male with HIV and disseminated tuberculosis experienced recurrent maculopapular eruptions with mucosal involvement after exposure to multiple medications, including fluoroquinolones and rifampicin.
Determination of diagnostic cycle threshold cutoffs for qPCR-based prevalence surveys of soil-transmitted helminth infections.
This analysis of pre-intervention, population-based surveys within the DeWorm3 community-based cluster-randomized trial used high-throughput qPCR results from 29,980 samples to define cycle-threshold cutoffs for…
A systematic review of digital healthcare-associated infection surveillance methods - comparisons and considerations for future program design.
This systematic review examined original hospital-based research on digital healthcare-associated infection (HAI) surveillance, identifying clinical and technical design elements and reported impacts.
Real-world implementation and impact of interventional antimicrobial stewardship programmes in Asian hospital settings: an updated systematic review mapped to IDSA/SHEA recommendations, the WHO Bacterial Priority Pathogens List, and AWaRe antibiotic categories.
This updated systematic review examined adult inpatient interventional antimicrobial stewardship studies in Southeast and East Asia, mapping programme components and outcomes to IDSA/SHEA recommendations, WHO AWaRe…
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