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1064 articles
September 202624
Effectiveness and moderators of PE and CPT in adult PTSD treatment: a systematic review and meta-analysis.
This meta-analysis evaluated the effectiveness of Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT) for treating PTSD, synthesizing data from 175 treatment arms across 163 studies.
Daratumumab Treatment in Severe Anti-NMDAR Encephalitis: Two Case Reports and Literature Review.
Two patients, aged 21 and 19, presented with severe anti-NMDAR encephalitis, exhibiting neuropsychiatric symptoms, seizures, and dysautonomia. Both required ICU care and did not improve after multiple immunotherapies.
Protocol for project FIERCE: A randomized controlled trial to evaluate a positive emotion-focused meditation intervention for physicians with elevated stress.
This randomized controlled trial will assess the feasibility and efficacy of a six-week mindfulness intervention, the Building Emotional Strength Training (BEST) program, for 90 full-time physicians experiencing…
Relational care in community mental health: Evaluating staff experiences in Intensive Community Care Services (ICCS) vs treatment as usual.
This randomized controlled trial evaluated staff experiences in Intensive Community Care Services (ICCS) compared to Treatment as Usual (TAU) in community mental health.
Transcranial Magnetic Stimulation for Patients with Exposure Therapy Resistant Obsessive-Compulsive Disorder (TETRO): Study Protocol for a Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial investigates the efficacy and cost-effectiveness of low-frequency (1Hz) rTMS targeting the pre-SMA as an adjunct to exposure therapy in adults with OCD who have not responded…
Mechanisms of impact of mental health peer support in high-, middle- and low-income settings: mediation analysis of the UPSIDES randomised controlled trial.
This multicenter randomized controlled trial examined the mechanisms of peer support (PS) in improving recovery outcomes among 565 adults with severe mental health conditions across various income settings.
No evidence for a generalised predictive processing deficit in psychosis: A meta-analysis.
This meta-analysis evaluated the predictive processing theory of psychosis by analyzing 34 results from 27 studies involving 904 individuals with schizophrenia-spectrum psychosis and 1,039 healthy controls.
Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.
This systematic review examined barriers and facilitators to implementing pharmacogenomic (PGx) testing for antidepressant use in primary care, utilizing the Consolidated Framework for Implementation Research (CFIR).
Where does the "ἀφημί" (speechless) in nfvPPA come from?: a case study on phonological retrieval and the potent effect of moraic assistance.
A 65-year-old Japanese male with non-fluent/agrammatic variant primary progressive aphasia (nfvPPA) presented with severe speechlessness.
Long-term safety and efficacy of vornorexant in Japanese patients with insomnia: A 52-week open-label, randomized trial.
This multicenter, randomized, open-label trial evaluated the long-term safety and efficacy of vornorexant in 371 Japanese patients with insomnia over 52 weeks.
Polysubstance use after remission in first-episode psychosis: Associations with positive symptoms and self-care.
This analysis of the HAMLETT randomized controlled trial examined substance-use patterns and their associations with symptoms, cognition, and functioning 3 to 6 months after remission in people with first-episode…
Exploring the experiences, views, and needs of family members of emergency response workers: a systematic review and meta-synthesis.
This systematic review and meta-synthesis examined the experiences and needs of family members of emergency responders, identifying significant emotional and practical burdens they face.
A Smartphone-Based Ecological Momentary Intervention for Workplace Mental Health: Randomized Controlled Trial.
This randomized controlled trial evaluated the effectiveness of Neurum, a smartphone-based intervention, in reducing workplace stress among 201 working adults over four weeks.
Rapid plaque clearance with anti-amyloid therapy for Alzheimer's disease: in consideration of donanemab treatment duration from real-world cases.
Two patients with early-stage Alzheimer's disease were treated with donanemab, achieving complete amyloid clearance as assessed by amyloid PET scans before their 6th and 9th infusions.
Are co-occurring behavioural health risk factors related to reach and efficacy of in-person versus computer-generated brief alcohol interventions? Findings from a randomized controlled trial.
This randomized controlled trial examined the impact of co-occurring behavioral health risk factors (HRFs) on the reach and efficacy of brief alcohol interventions among 961 at-risk alcohol users in a hospital setting.
Effect of dopamine partial agonist antipsychotics on suicide risk in persons with schizophrenia and schizoaffective disorders: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dopamine partial agonist antipsychotics (DPAs) affect suicide outcomes in people with schizophrenia or schizoaffective disorders.
Efficacy and safety of cannabinoid-based interventions for behavioral and cognitive symptoms in dementia: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of cannabinoid-based interventions for behavioral and cognitive symptoms in dementia, analyzing nine randomized controlled trials with 334…
Delusional infestation in Parkinson disease: a case report of medication-induced psychosis.
A 66-year-old woman with Parkinson disease developed visual and tactile delusions of a parasitic infestation while on dopaminergic therapy.
Dose-response meta-analysis of dual orexin receptor antagonists on sleep parameters and implications for orexin-mediated arousal.
This meta-analysis evaluated the dose-response effects of dual orexin receptor antagonists (DORAs) on sleep parameters in adults with insomnia disorder.
Glymphatic system alterations in schizophrenia evaluated by the DTI-ALPS index: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed glymphatic-system function in schizophrenia using the DTI-ALPS index, a surrogate marker, across eight studies comparing patients with healthy controls.
Extended Long-Term Effects of Cognitive and Aerobic Training on Cognitive Function in Patients With Stress-Related Exhaustion Disorder: A 4.5-Year Follow-Up of a Randomized Controlled Trial.
This randomized controlled trial assessed the long-term effects of computerized cognitive training (CCT) and aerobic training (AT) on cognitive function in patients with stress-related exhaustion disorder, 4.5 years…
Implementation of Mobile Health Intervention Targeting Belongingness and Burdensomeness: An Ecological Momentary Assessment Study of Self-Injurious Thoughts and Behaviors in LGBTQ+ Individuals.
This randomized controlled trial evaluated a mobile health intervention aimed at reducing self-injurious thoughts and behaviors in LGBTQ+ individuals.
Navigating Social Media: Balancing Connectivity With Media Literacy to Combat Misinformation and Protect Mental Well-Being.
This systematic review examines the relationship between social media use, misinformation, and mental health impacts, particularly psychiatric misinformation.
Testing How Mindfulness Skills Change for Novice Meditators Using Headspace: Examining Trait Mindfulness and Perceived Stress as Moderators.
This randomized controlled trial examined the impact of the Headspace app on mindfulness skills in novice meditators over 8 weeks.
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